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Ginkgo Biloba Folium Extract

Ginkgo Biloba Folium Extract

Ginko Biloba Extract (GBE) is a kind of product enriched with active ingredients extracted from the leaves of Ginkgo biloba (Ginkgo biloba L.) as raw materials and using appropriate solvents.

PRODUCT INTRODUCTION

PRODUCT INTRODUCTION

Xi'an JinRui International Trade Ltd

 

 

Xi'an JinRui International Trade Ltd. Founded in Hong Kong in 2010, YSG is a holding company of one companies.The company is Sanyuan Jinrui Natural Ingredients Co., Ltd., a company dedicated to the research, development and production of professional and specialized plant extracts. Jinrui's production and process base is located inside the Sanyuan County Qinghe Food Industrial Park.

 

Why Choose US

 

Our Factory
Jinrui's production and process base is located inside the Sanyuan County Qinghe Food Industrial Park. Established in 2006, the base occupies a plot of 26,000 square meters and takes full advantage of the "plant gene database" that is the nearby Qin Mountains. Using plants as natural raw materials and cutting-edge technology for the extraction process, Jinrui is well-known as one of the country's foremost plant extraction producers.

 

Our Product
With advanced production equipment and a complete quality inspection system, it provides high-quality natural products for industries such as health food, health care products, cosmetics, medicines, and feed. And technical services, established stable sales channels around the world.

 

Our Certificate
Our products have passed the US FDA registration, Kosher certification, Halal certification, ISO9001 certification, HACCP certification, and have obtained SC production license, health food business license, and export food production enterprise registration.

 

Our Service
The company always adheres to the principle of quality first and honesty, and sincerely cooperates with you with high-quality products and excellent services.

 

Ginkgo Biloba Folium Extract

Ginkgo Biloba Folium Extract

Ginkgo Biloba Folium Extract is a class of active compounds extracted from Ginkgo biloba leaves with solvents. are important natural products. Its main active ingredients are flavonoids and terpene lactones.

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What is Ginkgo Biloba Folium Extract

 

Ginko Biloba Extract (GBE) is a kind of product enriched with active ingredients extracted from the leaves of Ginkgo biloba (Ginkgo biloba L.) as raw materials and using appropriate solvents. Various preparations made with GBE as raw materials are widely used in medicine, health care products, food additives, functional beverages, cosmetics and other fields. Ginkgo Biloba Extract is well known for its medical value. The extract is rich in terpenoids, flavonoids, and proanthocyanidins, which have antioxidant, anti-inflammatory, vasodilatory, and platelet inhibitory effects.

 

Advantages of Ginkgo Biloba Folium Extract

1. Good for angina.


2. Beneficial for vertebrobasilar insufficiency.


3. Beneficial for Alzheimer's.


4. Beneficial for tinnitus improvement.

5. Beneficial for acute mountain sickness.

6. Prevent or improve dementia.

7. Improve memory and concentration (for those in good health).

8. Improving peripheral arterial disease: intermittent claudication.

9. Prevent or improve with stroke.

10. Improve tardive dyskinesia.

11. Powerful antioxidant properties, large amount of flavonoids and terpenoids in ginkgo biloba have strong effect of scavenging free radicals.

12. Promote vasodilation to increase blood flow and improve blood circulation.

13. Improve cardiovascular and cerebrovascular health.

14. Prevention and treatment of Alzheimer's disease.

 

Three Major Effects of Ginkgo Biloba Folium Extract in Cosmetics
 

Skin whitening
Our endocrine is easily disordered and unbalanced when the body is in a bad state. At this moment, there are too many oxygen free radicals , while the superoxide dismutase (SOD) is insufficient, resulting in excessive oxygen free radicals and dermal layer cells to produce oxidation, a large amount of lipofuscin (lipid peroxide) is formed, causing melasma or pregnancy spots.
The flavonoids contained in ginkgo biloba can hinder the formation and deposition of pigments in the dermis, whitening the skin and preventing pigmented patches.In addition to flavonoids, trace elements such as manganese and molybdenum in ginkgo leaves can also scavenge oxygen free radicals and inhibit the growth of melanin.

 

Obesity-fighting effects
With the gradual improvement of people's living standards, there are more obese people. Many people hope to adopt more convenient and effective ways to lose weight, such as applying weight-loss cosmetics to fat deposits, such as legs, buttocks, and abdomen , To achieve the purpose of weight loss.
That substances containing anti-phosphodiesterase activity can reduce localized fat. The diflavonoids in ginkgo biloba have the effect of antagonizing the activity of phosphodiesterase. Therefore, the weight-loss cream or soap-reducing soap based on Ginkgo Biloba Folium Extract can partially eliminate the dead fat and achieve weight lossing and bodybuilding.

 

Efficient spectroscopic bactericidal killing
That Ginkgo Biloba Folium Extract has a spectral bactericidal effect, it has obvious inhibitory effects on common pathogenic bacteria that infect the skin such as Staphylococcus aureus, Pseudomonas aeruginosa and Epidermal flocculus. this kind of bacterial action can be shown at very low concentrations. the high-efficiency antibacterial feature is extremely advantageous for it as a functional raw material for cosmetics.

 

Features of Ginkgo Biloba Folium Extract

 

 

Anti-aging effect: After taking it, most patients can delay the growth of fine lines and wrinkles, make the skin more youthful, and restore the original activity and elasticity of the skin.

 

Enhance the antioxidant function of the brain: Ginkgo Extract can effectively increase the excitement of the brain, and also can remove free radicals deposited in the body, and can also prevent the occurrence of Alzheimer's disease.

At the same time, it can improve the symptoms of dryness, fatigue and tearing of the eyes, and can also prevent the recurrence of eye diseases. Some patients can also treat dizziness and nausea caused by high blood pressure after taking it, effectively improve blood microcirculation, and can also shrink and expand blood vessels. At the same time, Ginkgo Extract can play a role in the treatment of diabetes, effectively regulate insulin in the body, and can also prevent the recurrence of diabetes, and can also play a role in regulating blood sugar and improving insulin resistance.

 

Ginkgo Biloba Standardized Extract

Antiviral activity of Ginkgo Biloba Folium Extract

 

The broad‐spectrum antiviral activity of EGb and its impact on viral life cycle stages, such as viral binding, viral entry, expression of proteins, as well as assembly and release of proteins. This antiviral activity is mainly observed under the cytotoxic threshold. EGb is also known to have an inhibitory effect against influenza A and B viruses via disruption of the hemagglutinin (HA) to the host cells.

The influenza A virus depends on the interactions between HA and neuraminidase (NA) with sialic acid present in the cell surface receptor. Ginkgetin, a natural biflavone isolated from GB, can effectively block the sialidase activity of the influenza virus, thus preventing viral adsorption on the host's cell surface. Furthermore, EGb has been found to have a substantial antiviral effect against the H3N2 influenza virus as well as the hepatitis B virus.

 

The antiviral effect of GB to be due to the disruption of viral fusion and the protective effect induced by GB on the host cells by improving its stability and reducing its permeability. Furthermore, studies showed that isorhamnetin, a flavonoid present in EGb, can inhibit NA and HA found in the H1N1 virus. This flavonoid also reduced autophagy induced by a viral infection, production of reactive oxygen species, and the phosphorylation of mitogen-activated protein kinase.

Ginkgo Biloba Extract Powder

 

Forms of Taking Ginkgo Biloba

 

 

Capsules and tablets: These are the most common forms of ginkgo biloba. They are convenient to use and easy to dose. They also have no smell or taste, which makes them pleasant to take. However, they may contain some additives and binders that are not always natural.

 

Extracts: These are liquid forms of ginkgo biloba that can be added to water or other beverages. They usually have a faster effect because they are rapidly absorbed into the bloodstream. However, they may contain a high concentration of active substances, which can be dangerous if the recommended dose is exceeded.

 

Tea: This is a form of ginkgo biloba that can be made from fresh or dried ginkgo biloba leaves. Tea contains natural antioxidants and may be beneficial for improving heart and circulatory system health. However, the effects of tea may be less noticeable than those of other forms of ginkgo biloba, and dosing may be unstable.

In general, the choice of ginkgo biloba form depends on individual needs and preferences. It is recommended to consult your doctor or pharmacist for advice on choosing the most appropriate form of ginkgo biloba for you.

 

Interactions of Ginkgo Biloba Extract with Other Drugs

 

Ginkgo biloba extract is a natural remedy that can affect the metabolism and action of other drugs. Therefore, before using ginkgo biloba extract, it is necessary to consult a doctor to avoid possible interactions with other drugs.


The interaction of ginkgo biloba extract with anticoagulants (for example, Warfarin) can lead to an increase in their action, which can lead to bleeding.


Also, ginkgo biloba extract can interact with drugs that are used to treat depression (for example, sertraline) and bipolar affective disorder, enhancing their effect.


In addition, ginkgo biloba extract can interact with drugs that are used to treat Alzheimer's disease and dementia, such as donepezil and galantamine, enhancing their action.


Finally, ginkgo biloba extract may interact with certain blood pressure-lowering drugs, such as nifedipine and verapamil. This can lead to an increase in the action of drugs and a decrease in blood pressure.
In general, before using ginkgo biloba extract in combination with other drugs, you should consult a doctor.

 

Preparation Process of Ginkgo Biloba Extract

 

 

A preparation process of ginkgo biloba extract and the water-soluble ginkgo biloba extract and belongs to the technical field of traditional Chinese medicine preparations. The preparation process of the ginkgo biloba extract is characterized in that fat-soluble ginkgo biloba extract is adopted as a raw material, and 22%-28% hot ethyl alcohol is adopted as an extracting solvent. The process is efficient, safe, convenient and fast to use and economical, 100% of the water-soluble extract obtained through the process is dissolved in water, and the effective ingredient of the extract comprises 24% to 27% of brass, 6% to 8% of testolactone and 5 parts per million (5 ppm) or less of ginkgolic acid. Oral liquid prepared from the ginkgo biloba extract is transparent and free of sediment and suspended solids and can be absorbed by the human body easily, and the bioavailability is at least 20% higher than that of a common solid preparation.


This blending process for constant quality can be regarded analogous to wine blends referred as cuvée. The blend of G. biloba leaves is extracted by 60% (m/m) aqueous acetone. After separation of the primary extract from the exhausted plant material, acetone is removed by evaporation to leave an aqueous solution. This aqueous solution is cooled while stirring to induce a precipitation of chlorophyll, biflavones and the major bulk of ginkgolic acids, which represents the second waste stream. After removal of the precipitate, the residual aqueous solution is loaded with ammonium sulfate and extracted with a mixture of acetone and methylethylketone in a countercurrent fashion. While pure water and acetone are able to mix in any ratio, they effectively separate using highly kosmotropic salts like ammonium sulfate. The resulting aqueous phase represents another waste stream.

 

The acetone-methylethylketone phase is highly concentrated by evaporation of the solvent and subsequently diluted with water. This resulting, mainly aqueous solution is extracted by butanol, however, in this case in a multiple static fashion, since butanol and water need a lot of time to separate thoroughly. The aqueous phase is the next waste stream, while the butanol phase is again highly concentrated by evaporation of the solvent and subsequently diluted with water. This resulting mainly aqueous solution is extracted with heptane, to remove essential oils and the last remaining traces of ginkgolic acids, and achieve the ≤5 ppm specification. The heptane phase is the last waste stream of the process, however, like the other organic solvents in the process, it is recycled continuously to minimize consumption of hydrocarbons. The mainly aqueous phase is concentrated by evaporation of the solvent and dried to yield the final extract.

 

Precautions for Using Ginkgo Biloba Folium Extract
Best Ginkgo Biloba Extract
Ginkgo Biloba Extract Powder
Ginkgo Biloba Standardized Extract
Ginkgo Biloba Leaf Powder

1. Do not use it for women who are trying to conceive or during pregnancy, as it may cause difficulty in conception, premature birth, or bleeding during childbirth.

 

2. Not to be used by breastfeeding women, as the safety is unknown.

 

3. Do not use it in epilepsy patients, it may increase the risk of disease.

 

4. Ginkgo fruit and pulp can cause severe allergic skin reactions and mucous membrane irritation.

 

5. People who have been allergic to poison ivy, poison oak, poison sumac, mango rind, or cashew shell oil may also have an allergic reaction to Ginkgo Biloba.

 

6. Glucose-6-Phosphate Dehydrogenase deficiency should not be used in patients with acute hemolytic anemia.

 

7. Please stop using ginkgo-related products two weeks before surgery, because ginkgo may delay blood clotting and increase the risk of bleeding during and after surgery.

 

8. Do not use drugs with anticoagulant effects or those with abnormal coagulation function, which may increase the risk of bruising or bleeding. This is due to the anticoagulant effect of Ginkgo biloba. Common related drug names are: Aspirin, clopidogrel, diclofenac, ibuprofen, naproxen, dalteparin, enoxaparin, heparin, warfarin.

 

9. Do not use in combination with commonly used psychiatric drugs, which may affect the efficacy of the drug. Commonly related drug names are: Alprazolam, Buspirone.

 

10. Do not use in combination with the anti-human immunodeficiency virus (also known as HIV) drug Efavirenz, which may affect the efficacy of the drug.

 

11. Do not use in combination with St. John's wort and antidepressant fluoxetine, which may cause hypomania (symptoms: irritability, nervousness, restlessness, and excitement).

 

12. Do not use in combination with drugs that need to be metabolized by Cytochrome P450 enzymes, which may affect the efficacy of drugs. Commonly related drug names are as follows:
Clozapine), cyclobenzaprine, fluvoxamine, haloperidol, imipramine, mexiletine, olanzapine, pentazocine, propranolol, tacrine, theophylline, zileuton, zolmitriptan, Amitriptyline, carisoprodol, citalopram, diazepam, lansoprazole, omeprazole, phenytoin, warfarin, celecoxib, diclofenac, fluvastatin, glipizide, ibuprofen, irbesartan, losartanpiroxicam, tamoxifen, tolbutamide, torsemide, clozapine, codeine, desipramine, donepezil, fentanyl, flecainide, fluoxetine, meperidine, methadone, metoprolol, olanzapine, ondansetron, tramadol, trazodone, lovastatin, clarithromycin, cyclosporine, diltiazem, estrogens, indinavir, triazolam.

 

13. Do not use hypoglycemic drugs, which may affect the efficacy of the drug. Common related drug names are as follows: Glimepiride, glyburide, insulin, pioglitazone, rosiglitazone, chlorpropamide, glipizide, tolbutamide.

 

14. Do not use in combination with the antidepressant Trazodone. There have been cases of co-administration leading to coma.

 

15. Do not use in combination with drugs that increase the chance of seizures (such as anesthetics, theophylline, antiarrhythmic drugs, antibiotics, antidepressants, antihistamines, immunosuppressants, stimulants), which may greatly increase epilepsy risk of seizures.

 

16. Do not use in combination with antiepileptic drugs, which may affect the efficacy of the drug. The related drug names are: Phenobarbital, primidone, valproic acid, gabapentin, carbamazepine, phenytoin.

 

17. Do not use in combination with the antihypertensive drug Hydrochlorothiazide, which may cause blood pressure to rise.

 

18. Do not use in combination with Omeprazole, a drug for peptic ulcer or reflux esophagitis, as it may affect the efficacy of the drug.

Ginkgo Biloba Extract (GBE) is a kind of product enriched with active ingredients extracted from Ginkgo biloba L. Various preparations made from GBE are widely used in the fields of medicine, health care products, food additives, functional beverages, cosmetics, and so on.

 

FAQ

 

Q: What is Ginkgo biloba extract good for?

A: Ginkgo (Ginkgo biloba) is one of the oldest living tree species. It is also one of the best-selling herbal supplements in the United States and Europe. Ginkgo has a long history of use in treating blood disorders and memory issues. It is best known today as way to potentially keep your memory sharp.

Q: What is the use of Ginkgo Folium?

A: The HMPC concluded that ginkgo leaf medicines containing the dry extract can be used to improve the age-related cognitive impairment (worsening of mental abilities) and quality of life of adults with mild dementia.

Q: What happens if you take Ginkgo biloba every day?

A: In most cases, ginkgo biloba is considered safe when consumed daily in moderate amounts. However, it's important to contact your healthcare provider before use, especially if you have any existing medical conditions or are taking prescription medications or supplements.

Q: What is homeopathic medicine Ginkgo biloba used for?

A: Ginkgo biloba is an herb used to treat altitude sickness (prevention), cerebral vascular insufficiency, cognitive disorders, dementia, dizziness/vertigo, intermittent claudication, macular degeneration/glaucoma, memory loss, premenstrual syndrome, SSRI-induced sexual dysfunction, and as a vasodilator.

Q: What does ginkgo biloba do to the brain?

A: Ginkgo improves blood flow to the brain and acts as an antioxidant. These effects may translate into some benefits for certain medical problems, but the results have been mixed. Some studies have found that in healthy people, ginkgo might modestly boost memory and cognitive speed.

Q: What vitamins should I not take with Ginkgo Biloba?

A: Avoid using ginkgo together with other herbal/health supplements that can increase your risk of seizures. This includes EDTA, folic acid, GBL (gamma butyrolactone), GHB (gamma hydroxybutyrate), glutamine, hyssop oil, juniper, L-carnitine (levocarnitine), melatonin, rosemary, sage, wormwood, and others.

Q: What is the difference between ginkgo biloba and ginkgo biloba extract?

A: Ginkgo biloba extract (GbE) is a dietary supplement derived from an ethanolic extract of Ginkgo biloba leaves. Unfinished bulk GbE is used to make finished products that are sold as dietary supplements.

Q: How long does it take Ginkgo biloba to start working?

A: It takes about 4 to 6 weeks to see an effect once you start taking ginkgo biloba. And it's best to take it daily on a long-term basis for best results. Ginkgo biloba has drug interactions to consider and can worsen some health conditions.

Q: Is ginkgo biloba safe for the liver?

A: Abstract. Ginkgo biloba leaf extract has been shown to increase the incidence in liver tumors in mice in a 2-year bioassay conducted by the National Toxicology Program.

Q: Does Ginkgo Biloba help you sleep?

A: Tryptophan, ginkgo biloba, and L-theanine may also help promote sleep. However, they are not backed by many studies, so more research is needed before strong conclusions can be made.

Q: What is the best way to take ginkgo biloba?

A: As a nutritional supplement, or to achieve other therapeutic goals, the standard dose is 40 to 120mg, 3 times per day. Ideally, ginkgo supplements should be taken with meals, to allow for optimal absorption.

Q: How many months should I take ginkgo biloba?

A: Ginkgo biloba risks. Ginkgo is generally safe for healthy people to use in moderation for up to six months.

Q: Can you take fish oil and ginkgo?

A: Both supplements also support healthy blood flow, and ginkgo does so in part by increasing nitric oxide levels. If you're not concerned about blood thinning properties, you can take these supplements together; just be sure to do so with food.

Q: What is Ginkgo biloba extract good for?

A: Ginkgo (Ginkgo biloba) is one of the oldest living tree species. It is also one of the best-selling herbal supplements in the United States and Europe. Ginkgo has a long history of use in treating blood disorders and memory issues. It is best known today as way to potentially keep your memory sharp.

Q: What are the benefits of Ginkgo biloba homeopathy?

A: Ginkgo biloba is an herb used to treat altitude sickness (prevention), cerebral vascular insufficiency, cognitive disorders, dementia, dizziness/vertigo, intermittent claudication, macular degeneration/glaucoma, memory loss, premenstrual syndrome, SSRI-induced sexual dysfunction, and as a vasodilator.

Q: What is the use of Ginkgo Folium?

A: The HMPC concluded that ginkgo leaf medicines containing the dry extract can be used to improve the age-related cognitive impairment (worsening of mental abilities) and quality of life of adults with mild dementia.

Q: What happens if you take Ginkgo biloba every day?

A: In most cases, ginkgo biloba is considered safe when consumed daily in moderate amounts. However, it's important to contact your healthcare provider before use, especially if you have any existing medical conditions or are taking prescription medications or supplements.

Q: Does ginkgo biloba make you feel good?

A: Some studies suggest that ginkgo biloba may be helpful for relieving symptoms of anxiety. One study found that people who took 480 mg of ginkgo biloba each day experienced a 45% greater reduction in their anxiety symptoms than those taking a placebo. 5 Such results may be due to increased antioxidant levels.

Q: Does ginkgo biloba give you energy?

A: It's been widely studied as an anti-inflammatory herb for its platelet-forming and circulation-boosting effects. According to current research, ginkgo biloba benefits may include improved cognitive function, positive mood, increased energy, improved memory and reduced symptoms related to multiple chronic disease.

Q: When to take ginkgo biloba, morning or night?

A: Many individuals prefer taking Ginkgo Biloba in the morning, and for good reason. Starting your day with this supplement may provide an early cognitive boost. Here's why: Enhanced Alertness: Ginkgo Biloba is believed to increase blood flow to the brain, potentially improving alertness and mental clarity.

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