A drug called "Cepharanthine" has also recently become "hot" in academia. Two years ago, Chinese scientists discovered that it has high anti-coronavirus activity, and two years later, Canadian pharmaceutical companies finally started clinical trials. "Cepharanthin is an old drug used to treat leukopenia, and it showed higher anti-new coronavirus activity than other drugs such as redeliver on our screening platform." Beijing University of Chemical Technology School of Life Science and Technology Chang, Tong Yigang, Chinese team leader of the Animal and Environment Group of the China-WHO joint research expert team on the origin of the new coronavirus.
Cepharanthine
Stephania japonica, like Chinese medicine, comes from the roots or leaves of Stephania japonica, and one of its main active ingredients is Cepharanthine. It was first known for its function of promoting leukocyte production. Its basic principle: make the bone marrow tissue rapidly proliferate and stimulate the reticuloendothelial system, thereby greatly enhancing the hematopoietic capacity.
Of course, in addition to the functions mentioned above. It also has anti-inflammatory and analgesic properties. For the multidrug resistance of leukemia cells, CEP has the ability to partially reverse. On the market, as a classic reversal drug, verapamil, CEP is more effective than verapamil and has a little cytotoxic effect. Studies have also shown that CEP not only has a reversal effect on the multidrug resistance of blood cancer cells but also can better reverse the multidrug-resistant tumor cells. Relevant research results show that CEP can enhance the immune function of related macrophages and T cells in the human body.
Cepharanthine Covid 19
The patent specification published by Chinese scientists on May 10 shows that 10uM (micromol/L) of fenugreek inhibits the replication of coronavirus by a factor of 15,393. Compared with some previous coronavirus drugs, such as Molnupiravir, Paxlovid, VV116, etc., the effect of Cepharanthin is obviously better, and the R&D resources and R&D efforts invested by various countries are unprecedented. In the face of the surprise and fickleness of the new coronavirus, it may not take long to end the epidemic.
However, Cepharanthine currently has no relevant human trials, and it is still theoretical. It also needs the help of the country or powerful pharmaceutical companies, so that the theory can be transformed into clinical trial results as soon as possible, so as to help mankind completely defeat covid-19 and give mankind a clean and new world!
