Organic Phycocyanin Powder

What is Organic Phycocyanin Powder?

Organic Phycocyanin Powder is a photosynthetic pigment-protein complex obtained after separation and purification from microalgae cells. It is an auxiliary pigment of chlorophyll. Phycocyanin has been widely used in many fields. It can be used as a natural colorant in food and as an additive in the cosmetic industry. It can also be used as a nutritional supplement in the health care industry. 

Because of its high sensitivity to fluorescent reagents can also be used in immunolabeling experiments as a marker for antibodies and receptors. In addition, organic phycocyanin has biological activities such as anti-inflammatory, antioxidant, and immune regulation. It can also be made into anti-inflammatory agents, antioxidants, etc., and used in the pharmaceutical industry.

Structural features of Organic Phycocyanin Powder:

organic phycocyanin is composed of an open-chain tetrapyrrole chromophore, phycobilin, covalently attached to a protein molecule. The difference in the type and quantity of phycobilin chromophore will cause phycocyanin to show different colors. Changes in chromophore structure can cause phycocyanin discoloration and loss of antioxidant activity. 

Phycocyanin is located at the end of the peripheral rod, adjacent to a core cylinder composed of allophycocyanin. Its basic structure is composed of monomers composed of α and β 2 homologous subunits. These monomers oligomerize into (αβ)3 trimers to form symmetry with C3 face to face, and every two (αβ)3 forms one (αβ) 6. Hexameric structure with triple symmetry. The hexamers are further assembled into rods or stems, and non-pigmented connexins are sequestered in macropores in the center of trimers, hexamers, rods, or core cylinders.

How to improve the stability of Organic Phycocyanin Powder?

Phycocyanin is a water-soluble protein-pigment complex. The degradation rate of phycocyanin depends on the aggregation state of the protein, which is affected by other factors such as light, pH, and temperature. Therefore, it is necessary to improve its stability.

1. Add stabilizer

Adding stabilizers is the easiest way to improve the stability of phycocyanin. The method is easy to apply and does not require complex or expensive equipment. However, it is required that the stabilizer has high safety, low toxicity, and no harm, and the additive dosage is large. At present, the commonly used stabilizers are mainly sugar, sorbitol, benzoic acid, sodium azide, and dithiothreitol.

2. Chemical modification

Chemical modification is a technique that utilizes intramolecular or intermolecular bifunctional reagents to covalently bind two chemical groups on the surface of proteins. To strengthen the folded structure of phycocyanin and improve its stability. Formaldehyde, methylglyoxal, and propionate can be cross-linked with phycocyanin to stabilize the tertiary and quaternary structure of phycocyanin, thereby improving the stability of phycocyanin. Covalently via protein and polysaccharide

Linked to maintain the extended tetrapyridyl structure and thus maintain the color of the pigment.

3. Embedding technology

The main encapsulation methods include microencapsulation and liposome entrapment. Microencapsulation technology is a technology in which solid, liquid, and gas are used as core materials, and then natural or synthetic polymer materials are used as wall materials to form semipermeable or sealed tiny particles. Liposomes are microvesicles formed according to the tendency of phospholipid molecules to form stable lipid bilayer membranes in the aqueous phase, which can not only effectively improve the stability and solution dispersibility of the embedded substances in the inner layer, but also can be used in delivery and transportation. The system works to improve the functional effect of the active substance.

4. Other

Improving the stability of organic phycocyanin can also be achieved by methods such as high pressure. The high pressure causes phycocyanin to form a more compact protein structure and aggregate with changes in secondary structure.

organic phycocyanin Application:

As a natural water-soluble pigment, phycocyanin is widely used in the food, cosmetic and pharmaceutical industries.

1. Application in food

Due to the instability of phycocyanin to light and heat, its application in baked food is limited, and its application is currently mainly concentrated in dairy products, gelatinous sugars, and other foods.

2. Application in the medical field

Phycocyanin has sensitivity, biocompatibility, absorbability, and low toxicity to the human body. Acts as an antioxidant, and neuroprotectant, and also promote skin wound healing.

3. Other applications

Organic Phycocyanin Powder has advantages such as high fluorescence quantum yield, high molar extinction coefficient, and large Stokes shift, outperforming many synthetic dyes currently used. Phycocyanin now binds to immunoglobulins, protein A, and avidin to form fluorescent probes.

Where to buy Organic Phycocyanin Powder?

Phycocyanin is a natural pigment. It can be used as a colorant in the cosmetic industry, as an additive in food, and as an anti-inflammatory agent, antioxidant, immunomodulatory, and fluorescent detection probe in medicine. With the continuous deepening of research on phycocyanin, the market application of phycocyanin will be broader.

Please contact professional phycocyanin manufacturers directly through this page or medical@ysgcn.com

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