What is Acid Caffeic?
Acid Caffeic, also known as "3,4-dihydroxycinnamic acid" or "3,4-dihydroxybenzene acrylic acid". It is a natural phenolic compound with a hydroxyphenylene acid structure. Yellow crystals without crystal water can be precipitated from the ethanolic solution of caffeic acid. Crystals containing water of crystallization can be precipitated from its dilute aqueous solution.
The molecular formula is C9H8O10, the molecular mass is 180.16u, easily soluble in ethanol and hot water, and slightly soluble in cold water. In addition to its application in the food field, caffeic acid phenylethyl ester also has various pharmacological activities such as increasing white blood cells, platelets, antioxidant, anti-inflammatory, anti-cancer, and regulating DNA methylation levels, and has broad medicinal development prospects.
Items | Specification | Result |
Physicochemical Control | ||
Assay | ≥99% | 99.34% |
Appearance | Fine powder | Complies |
Color | Light yellow | Complies |
solubility | Soluble in ethanol, insoluble in water, solution clarified | Complies |
Coliform | ≤0.5% | Complies |
Heavy Metals | ≤10ppm | Complies |
As | ≤2ppm | Complies |
Pb | ≤1ppm | Complies |
Hg | ≤1ppm | Complies |
Microbiological Control | ||
Total Plate | ＜1000CFU/g | Complies |
Yeast & Mold | ＜25CFU /g | Complies |
Coliform | ＜10CFU /g | Complies |
How is Acid Caffeic synthesized?
Caffeic acid is an important pharmaceutical product and chemical raw material. Caffeic acid is mainly prepared by chemical synthesis, biosynthesis, etc.
There are two main methods of chemical synthesis:
The first one is 3,4-dihydroxybenzaldehyde obtained by chlorination and hydrolysis of piperonal (also known as jasmonaldehyde), which is then condensed with malonic acid to form caffeic acid. The second is to use catechol as raw material to react with formaldehyde first and then react with p-nitrosoxylidine to obtain 3,4-dihydroxybenzaldehyde, which is then condensed with malonic acid to form caffeic acid.
The pathways of biosynthetic preparation mainly include hydrolysis of chlorogenic acid and biotransformation of p-coumaric acid.
What are the main applications of Acid Caffeic?
1. Intermediates of caffeic acid
for organic synthesis.
2. Can be used safely in cosmetics
Has a wide range of bacteriostatic and antiviral activities. Absorbs UV rays. A low concentration is an auxiliary agent for inhibiting skin-type hair dyes, which is beneficial to enhance the intensity of the color.
3. Antibacterial and antiviral
caffeic acid phenylethyl ester has a broad antibacterial effect, but can be inactivated by protein in vivo. In vitro tests show that it has antiviral activity and has strong inhibitory effects on vaccinia and adenovirus. Followed by polio type I and parainfluenza type III virus.
4. Anti-venom
A dose of 3 micrograms of caffeic acid can completely inhibit 20 micrograms of rattlesnake venom phosphodiesterase, which is used as an antivenom.
Why choose caffeic acid?
The chemical structure of caffeic acid is relatively simple, the source is rich, the synthesis is easy, and the cost is low. And it has a variety of pharmacological activities such as antioxidant, leukocyte increase, platelet increase, antiplatelet, antioxidant, and cerebral protection. It has broad application prospects in the prevention and treatment of oxidative stress and inflammatory response-related diseases.
Where to buy Acid Caffeic?
Yansheng International Group Ltd. is a professional caffeic acid manufacturer. We always insist that good products come from good raw materials and standard extraction and processing technology and strict quality inspection. We have more than 16 years of production and R&D experience. are your trusted manufacturer. Please purchase caffeic acid extract directly through this page or medical@ysgcn.com
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