Melatonine Powder Product Introduction
Melatonine Powder (N-acetyl-5-methoxytryptamine, MT), also known as a pineal hormone, is an indole hormone secreted by the pineal gland. In recent years, a large number of experimental studies have shown that melatonin can calm hypnosis and regulate the sleep-wake cycle, which is highly correlated with sleep.


COA of melatonin powder bulk:
| Item | Specification | Results |
| Appearance | white to off-white crystalline powder | Conforms |
| Solubility | Slightly soluble in water, soluble in acetone, ethyl acetate, and methanol | Conforms |
|
ldentification |
IR | Conforms |
| UV | Conforms | |
| HPLC | Conforms | |
| Chloride and sulfate | ≤0.02% | <0.02% |
| Loss on drying | ≤1.0% | 0.07% |
| Residue on ignition | ≤0.1% | 0.03% |
| Melting point | 117C-120C | 119.2°C-1194C |
| Particle size | 98% through 80 mesh | Conforms |
| Total plate count | ≤100Oclu'g | <1000ctulg |
| Yeast&Mold | ≤100cfulg | <100cfulg |
| E.Coli | Negative | Negative |
| Salmonella | Negative | Negative |
| S.aureus | Negative | Negative |
| Residual solvent | Ethandi≤500ppm | 387ppm |
| Tap density | 20.45g/ml | 0.57g/ml |
| Bulk dens ity | ≥0.35g/ml | 0.47g/ml |
| Clarity and degree of opalescence of solution | Clear in the 1% melatonin solution of ethanol or chloroform | Conforms |
| Heavy metals | s10ppm | <10ppm |
| Pb | ≤1ppm | <1ppm |
| As | s1ppm | <1ppm |
| Hg | ≤0.1ppm | <0.1ppm |
| cd | ≤0.5ppm | <0.5ppm |
| individual impurity | ≤0.1% | 0.032% |
| Total impurities | ≤1.0% | 0.10% |
| Assay(on a dried basis) | 98.5%-101.5% | 99.63% |
Why does Melatonine Powder improve sleep?
A large number of studies have confirmed that melatonin can significantly increase the content of gamma-aminobutyric acid in the brain, and the content of gamma-aminobutyric acid plays an extremely important role in the regulation of the sleep-wake cycle.
Therefore, when the retinal neurons are stimulated from the outside and projected to the suprachiasmatic nucleus in the front of the hypothalamus through the retinal hypothalamic tract, the body will actively adjust the pineal gland, secrete MT rhythmically, and at the same time feedback information to the optic chiasm. MT receptors in the upper nucleus. And there are two ways to achieve the role of regulating the sleep-wake cycle:
1. melatonin powder bulk can activate MT1 and MT2 receptors to regulate sleep. Both MT1 and MT2 receptors are G protein-coupled receptors. MT1 mainly inhibits neuronal activity and regulates sleep; MT2 mainly induces changes in the sleep phase.
2. The secretion of MT is stimulated by light and changes in a circadian rhythm. The secretion of melatonin is low during the day and reaches a high peak at night. The rhythmic alternation of high peak and low trough of melatonin affects γ- The content of aminobutyric acid in the body is based on the conversion of high and low levels, and the effect of regulating the cycle of sleep and wakefulness is achieved.

Why do we need Melatonine Powder?
As social pressure increases day by day, lifestyle changes, and the occurrence of sleep disorders has seriously affected people's normal life and rest, resulting in fatigue, fatigue, difficulty concentrating, memory loss, and low immunity. According to the statistics of the World Health Organization, 27% of people suffer from various sleep disorders, including long sleep latency, easy awakening, and short sleep time.
Best Melatonine Powder Supplier
Yansheng International Group Ltd. is a biotechnology enterprise integrating formulation research and development and professional technical services. We have a number of professional and experienced R&D technicians and consultants and cooperate with a number of powerful institutions to provide enterprises with solutions and emerging technologies that meet the trends between countries. is your Melatonin manufacturer of choice.
Where to buy Melatonin?
You only need to contact the most professional melatonin manufacturers and suppliers directly through this page, and you can also directly contact medical@ysgcn.com to buy the best melatonin
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