Polygonum Cuspidatum Root Extract Powder Introduction:
The main active ingredient of Polygonum Cuspidatum Root Extract Powder is resveratrol. It was discovered as early as 1924. The substance was found in the genus Vitis in 1974. It is an antitoxin secreted by plants when they encounter stress or pathogen attack. The synthesis increases sharply during irradiation, mechanical damage, and fungal infection, so it is called phytoalexin.
And first of all, it is characterized as a substance that can produce its own resistance to stress. It is widely found in a variety of plants. It has important biological activities such as antiviral. At present, Polygonum Cuspidatum Root Extract has been listed as a health product in the United States, Japan, Canada, and other countries.

Specification
| Latin Name | Polygonum cuspidatum Sieb.et Zucc. |
| Specification | Resveratrol ≥ 98.00% |
| CAS | 501-36-0 |
| Chemical formula | C14H12O3 |
| Molecular weight | 228.24 |
| Appearance | White or off-white powder |
| Odor | Characteristic |
| Taste | Characteristic |
| Bulk density | 40-60g/100ml |
| Tapped density | 60-90g/100ml |
| Particle size | NLT 95% pass 80 mesh |
| Loss on drying | ≤ 5.00% |
| Residue on Ignition | ≤ 5.00% |
| Total Heavy Metals | ≤10ppm |
| Pesticides residue | ≤ 0.01mg/kg meets the requirement and its modifications |
| Total plate count | ≤ 1000cfu/g |
| Yeast & Mould count | ≤ 100cfu/g |
Yansheng International Group Ltd. is a professional Polygonum series products manufacturer, we provide you with better quality Polygonin, Resveratrol, Emodin, etc. We always insist on using better raw materials, strict standard processing technology, and advanced testing standards, just to provide you with the best products and services!
Please contact us to purchase Polygonum Cuspidatum Root Extract Powder through this website or medical@ysgcn.com.
Extraction and Purification:
Weigh a certain amount of Polygonum root powder. Add 70% ethanol at a ratio of 1:20. Ultrasound-assisted extraction at 50°C for 1 h. The solid-liquid two phases were separated, and the solution was rotary-steamed at 50°C until there was no alcohol smell to obtain the resveratrol extract.
Add 2 volumes of petroleum ether to the extract for extraction. The petroleum ether phase was collected. The extraction was repeated until petroleum ether was colorless. Rotary evaporation at 40°C
After petroleum ether, it was put into a blast dryer and dried at 50°C to obtain resveratrol.
Antioxidant mechanism:
①Polygonum Cuspidatum Root Extract Powder Resveratrol has the ability to scavenge hydroxyl, superoxide, and metal-induced free radicals. Can block the nitration of bovine serum albumin. Its scavenging peroxynitrite anion (ONOO-) EC50 value is 22.7μmol·L-1.
② can improve the activity of antioxidant enzymes.
③It can exert an antioxidant effect through the non-enzymatic antioxidant system of an animal body. GSH is an important molecule in the body to eliminate free radicals. In vivo experiments found that the blank control was used as a reference. The GSH level in the resveratrol group was 150% of that in the blank control. In vitro experiments showed that resveratrol increased the level of GSH in cells from 0. 2 to 0. 35mmol·mg - 1 protein.
Polygonum Cuspidatum Root Powder Application in cosmetics:
1. Anti-aging and oxidation
Acts as a natural antioxidant. It has a strong effect of scavenging free radicals and anti-lipid peroxidation. The antioxidant effect is stronger than traditional antioxidants such as vitamin C, butyl hydroxytoluene, and tocopherol. Also activates the silent information factor (SIRT1). Causes physiological changes that delay aging and prolong lifespan, most notably by 50%.
2. Inhibit oil production
Good adhesion to skin. And it can shrink large pores, tighten loose skin and reduce wrinkles. Prevents excess oil production in the skin.
3. Whitening
Polygonum Cuspidatum Root Powder can inhibit tyrosinase in melanoblasts to achieve a whitening effect. At a concentration of 0.5ug/ml, the inhibitory effect on tyrosinase is equivalent to that of arbutin at a concentration of 50μg/mL.
4. Treat acne
It also has anti-inflammatory and bactericidal effects. Suitable for the treatment of skin acne.

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