Pueraria Mirifica Root Extract

Pueraria Mirifica Root Extract Introduction

Pueraria Mirifica Root Extract is the root of the legume Pueraria lobata (Willd.) ohwi. It is a commonly used traditional Chinese medicine. It has the functions of relieving muscle and reducing fever, sedation and increasing coronary blood flow. Pueraria contains a variety of flavonoids, the main active ingredients are daidzein, daidzin, puerarin, puerarin-7-xyloside and so on. Its main component is puerarin, namely 8-β-D-glucopyranose-4,7-dihydroxyisoflavone.

Puerarin has the functions of dilating coronary and cerebral blood vessels, reducing myocardial oxygen consumption, improving myocardial contractile function, and promoting blood circulation. It is suitable for the treatment of coronary heart disease, angina pectoris, myocardial infarction, retinal artery and vein occlusion, sudden deafness and other diseases, and the effect is remarkable. Pueraria Mirifica Root Extract has a strong antioxidant effect, which can enhance the body's ability to defend against free radical damage, which provides strong evidence for pueraria root extract, especially puerarin in the treatment of cardiovascular and cerebrovascular diseases.

Specification

Pueraria Mirifica Extract Function&Application

1. Effects on smooth muscle

The daidzein in Pueraria Mirifica Root Extract has anti-acetylcholine effect, can significantly contract smooth muscle, and is considered to be the main component of pueraria's antispasmodic effect.

2. Effects on coronary circulation

Pueraria decoction, alcohol extract, total flavonoids and puerarin all have obvious effects of expanding coronary blood vessels, which can increase coronary blood flow and reduce vascular resistance.

3. Effects on myocardial infarction and arrhythmia

Pueraria alcohol extract, daidzein and puerarin have obvious anti-arrhythmic effects on aconitine and barium chloride-induced arrhythmia, and puerarin can also significantly shorten the arrhythmia time in rabbits induced by chloroform and epinephrine. It can significantly reduce the scope of myocardial infarction and is considered to be a β-adrenergic receptor blocker.

4. Effects on cardiac function and myocardial metabolism

Pueraria total flavonoids and puerarin can slow down the heart rate, reduce the total peripheral resistance of the heart, reduce myocardial oxygen consumption, and improve myocardial work efficiency. Pueraria Mirifica Root Extract's active ingredient puerarin can also significantly reduce the production of myocardial lactic acid caused by ischemia and improve the metabolism of infarcted myocardium.

5. Effects on blood pressure and peripheral blood vessels

Total puerarin and puerarin can significantly reduce plasma renin activity and angiotensin, and lower blood pressure. Puerarin has obvious improvement effect on microcirculation disorder, which is mainly manifested in increasing the amplitude of microvascular movement and improving local microblood flow; total flavonoids of puerarin can significantly expand cerebral blood vessels and improve cerebral microcirculation and peripheral circulation.

6. Inhibit platelet aggregation

Pueraria Mirifica Root Extract puerarin inhibits adenosine diphosphate (ADP)-induced and 5-HT (serotonin) combined with ADP-induced platelet aggregation in humans and animals. In addition, puerarin can significantly inhibit the release of 5-HT in platelets induced by thrombin, and has an antithrombotic effect.

7. The effect of lowering blood sugar

Pueraria Mirifica Extract can resist the blood sugar-raising effect of adrenaline and has a certain blood sugar-lowering ability.

8. Effects on body temperature

The total flavonoids of Pueraria lobata have a lasting and obvious cooling effect on the increase of body temperature caused by endotoxin, and are commonly used in clinical symptoms of exogenous fever.

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