What is Polygonum Cuspidatum Extract Polydatin?
Polygonum Cuspidatum Extract Polydatin(PD), the chemical name is 3,4',5-trihydroxystilbene-3-B-D-glucoside, also known as resveratrol glycoside, is a kind of polydatin extracted and isolated from the plant Polygonum cuspidatum Stilbene compound, white needle-like crystalline powder, molecular formula C20H22O8, molecular weight 390.384.
In recent years, relevant scholars at home and abroad have conducted a lot of research on the pharmacological effects and mechanisms of PD and found that PD not only protects the liver and kidney, but also improves bone marrow, anti-fibrosis, regulates glucose metabolism, lipid metabolism, anti-inflammatory, relieves asthma, and promotes wound healing. and other pharmacological activities; and can protect the cardiovascular and cerebrovascular, protect nervous system, and show unique effects on the nervous system and cardiovascular system; in addition, PD has inhibitory effects on a variety of tumor cells, and can inhibit tumor cells through multiple targets and multiple pathways. Proliferation, induce tumor cell apoptosis and play an anti-tumor effect.
Specification:
Product Name | Polygonum Cuspidatum Extract Polydatin |
Latin Name | Polygonum cuspidatum Sieb.et Zucc. |
Specification | Polydatin ≥ 98.00%;99.009% |
CAS | 65914-17-2 |
Chemical formula | C20H2208 |
Molecular weight | 390.40 |
Protective effect on cardiovascular and cerebrovascular
Anti-fibrotic
Studies have found that PD can inhibit the proliferation of hepatic stellate cells HSC-T6 by inhibiting the sphingosine kinase 1 (SphK1) signaling pathway, thereby inhibiting liver fibrosis.
Regulates glucose and lipid metabolism
In terms of glucose metabolism regulation, the results of in vitro experiments suggest that PD intervention can increase the activity of islet cells, improve cell apoptosis, and reduce oxidative stress damage, thereby protecting islet β cells damaged by tetraoxtridine.
Anti-inflammatory effect
As a classic pathway of inflammation, the NF-KB pathway is widely involved in the body's immune response, inflammatory response, and other physiological processes, and regulates many genes related to inflammation.
Anti-tumor effect
Studies have shown that PD is effective against glioblastoma cells GBM, human osteosarcoma cells MG-63, multiple myeloma cells MM, nasopharyngeal cancer cells CNE-1, human cervical cancer cells He La, lung cancer cells A549 and other cancer cells. They all exhibit inhibitory effects, mainly through inhibiting cell proliferation, arresting the cell cycle, and inducing apoptosis.
Where to buy Polygonum Cuspidatum Extract Polydatin?
Yansheng International Group Ltd. is a professional Polygonin manufacturer, we provide you with better Polygonin, Polygonum extract, Resveratrol, etc. Please contact us directly through this website or medical@ysgcn.com to purchase Knotweed series products.
Hot Tags: polygonum cuspidatum extract polydatin,Polygonum Cuspidatum Polydatin,China, suppliers, manufacturers, factory, wholesale, quotation, low price, in stock, buy discount, free sample, made in China
