andrographis paniculata leaf extract Introduction:
The main active ingredient of andrographis paniculata leaf extract is andrographolide. It was first isolated from Andrographis paniculata in 1896. In 1911, it was confirmed that the ingredient was a lactone substance. Its main pharmacological activities are anti-allergic, anti-HIV virus, anti-inflammation, and anti-infection effects. It is extracted from Andrographis paniculata (Burm .f.) Nees. It is a traditional Chinese medicine with a long history of use. Because it is actually a pure natural plant and has the reputation of natural antibiotics. Therefore, its development prospects and applications are very worth looking forward to.
| Product Name: | Andrographolide | Plant Part: | Root(Or Leaf) |
| CAS | 5508-58-7 | Extraction: | Water&Ethanol |
| ANALYSIS | SPECIFICATION |
| Appearance | White powder |
| Odor | Bitter |
| Assay(Andrographolide, HPLC) | ≥10% 98% |
| Identification | Positive reaction: Be purple-red colored after reaction with an alkaline solution of DTBN |
| Other Lactones | No spots when flecked |
| Loss on drying | ≤1.0% |
| Residue on ignition | ≤0.1% |
| Heavy Metal | <10ppm |
| As | <2ppm |
| Residual Solvents | Eur.Pharm. |
| Total Plate Count | <1000cfu/g |
| Yeast & Mold | <100cfu/g |
| E.Coli | Negative |
| Salmonella | Negative |
Andrographolide has a high content in Andrographis paniculata, with extensive resources and little toxicity and side effects. Therefore, its research and use are increasing day by day. If you are wondering where to buy it? And how to use it? Just contact us through this website or directly contact medical@ysgcn.com
andrographis paniculata leaf extract Benefits:
Antipyretic:
Pure Andrographis Paniculata Extract has the effect of lowering and slowing down the increase in body temperature caused by pneumococcus and hemolytic beta streptococcus. Andrographolide tablets have a good antipyretic effect on endotoxin-induced fever and respiratory tract infection fever.
Anti-pathogenic microorganisms
Clinical studies have shown that the Chuanhuning injection has a significant curative effect in the treatment of respiratory viral infections, and is an effective traditional Chinese medicine injection that can treat both the symptoms and the symptoms of viral infections. Andrographolide has antagonistic effects against the Hong Kong virus (HKV), Ebola virus (EBOV), and respiratory syncytial virus (RSV).
Anti-inflammatory
Andrographolide has good anti-inflammatory effects both in vitro and in vivo.
Antibacterial
Andrographolide has an obvious antibacterial effect and has a good effect on various bacterial infections. It has fewer side effects than antibiotics and does not create more resistant strains.
Treat cardiovascular disease
Andrographolide has anti-myocardial ischemia, anti-ischemia-reperfusion injury, anti-platelet aggregation, protection of vascular endothelial cells, lipid regulation and blood pressure reduction, anti-atherosclerosis, prevention of restenosis after angiogenesis and improvement of blood rheology, etc.
Anti-fertility
Andrographolide also has an effect on the formation of male sperm. Animal experiments show that after the administration of andrographolide, sperm motility and sperm count are reduced; most sperm in the vas deferens are incompletely differentiated, and the vas deferens epithelium is completely destroyed. Therefore, pregnant couples and pregnant women are advised not to use andrographolide-containing drugs.
Andrographolide also has the effect of protecting the liver and gallbladder, treating endometriosis, immunomodulating, protecting against radiation-induced lung injury, relieving diarrhea, and treating obesity.
Natural antibiotic:
The study found that andrographis paniculata leaf extract andrographolide had a good anti-Pseudomonas aeruginosa (Perugino) biofilm effect. It has a synergistic antibacterial effect with azithromycin. Therefore, clinical combined use can reduce the dose and increase the efficacy, and reduce the adverse reactions to the drug. And the comprehensive effect of andrographolide is better than that of azithromycin.
Has a quorum-sensing inhibitor-like effect on Pseudomonas aeruginosa.
It can exhibit its anti-infective effect by promoting the function of phagocytes, that is, regulating the body's non-specific immune function.
Andrographolide is effective in treating acne caused by Propionibacterium. Studies have shown that it can have a therapeutic effect on acne by inhibiting the release of inflammatory factors. Therefore, it can be used as one of the effective components of cosmetic products for acne.
The anti-Candida Albicans biofilm effect is remarkable. Not only has low cytotoxicity in human tissue, but also can make Candida albicans biofilm cells apoptotic, and intervene in Candida albicans biofilm dispersed cells through apoptosis.
andrographis paniculata leaf extract Application:
1. It is mainly used in the field of medicine
2. It can also be used in the healthcare industry
3. Applied in the field of cosmetics
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