Beta Ecdysterone Powder manufacturer
Yansheng International Group Ltd. is the best Beta Ecdysterone Powder manufacturer, we always insist on providing the best products and services to customers all over the world! If you want to buy ecdysterone, please contact medical@ysgcn.com
Beta Ecdysterone Powder Product Information
Beta Ecdysterone Powder, also known as ecdysterone, 20-hydroxyecdysone (β-ecdysterone, 20-hydroxyecdysone), is a naturally occurring steroid component, usually found in herbs, insects and some aquatic animals, herbs Most abundant in plants. Molecular formula C27H44O7. Its structure has a cis (5β-) fused A/B ring, a 7-en-6-one chromophore and a 14α-hydroxyl group, 19 to 20 carbon atoms and a large number of substituents.
COA of Beta Ecdysterone Powder:
Benefits of Beta Ecdysterone Powder:
Cardiovascular effects
1. Inhibit apoptosis
Apoptosis is an important factor in the occurrence of cardiovascular diseases. β-ecdysterone can inhibit the increase of vascular endothelial cell intercellular adhesion molecule (ICAM-1) expression caused by arsenite and can inhibit endothelial cell apoptosis to a certain extent.
2. Inhibit oxidative stress
Oxidative stress plays a crucial role in the development and progression of cardiovascular disease. β-Ecdysterone can inhibit endoplasmic reticulum stress and attenuate hydrogen peroxide-induced cardiomyocyte injury.
3. Antiarrhythmic
beta ecdysterone bulk powder can reduce ventricular premature beat and arrhythmia induced by myocardial ischemia-reperfusion in rats, and reduce serum lactate dehydrogenase (LDH), aspartate aminotransferase (AST) and creatine in rats The activity of phosphokinase isoenzyme (CK-MB), its mechanism may be to reduce free radical damage and increase the permeability of myocardial cell membrane to ions.
4. Improve acute myocardial infarction
Other benefits:
1. Promote nucleic acid and protein synthesis
This is the most remarkable pharmacological activity of β-ecdysterone. Studies have shown that β-ecdysterone is the best ecdysteroid for promoting protein synthesis, and can increase protein synthesis in skeletal muscle cells by 20% by inhibiting the activity of phosphatidylinositol kinase-3 (PI-3K).
2. Effects on glucose metabolism
Disorders of glucose metabolism are still a thorny problem in the medical field. Studies have shown that β-ecdysterone can induce the expression of hepatic glucokinase and increase the glycogen reserve in the liver, thereby reducing the blood glucose level in mice with type 1 diabetes.
3. Effects on the central nervous system
Numerous studies have shown the protective effect of beta ecdysterone bulk powder in the central nervous system, and β-ecdysterone protects nerve cells through various pathways.
4. Effects on skeletal development
Studies have shown that β-ecdysterone delays the degeneration of articular cartilage cells by affecting the expression of collagen and metalloproteinases in knee cartilage cells. β-ecdysterone may alleviate osteoporosis and treat glucocorticoid-induced osteoporosis by inhibiting bone loss and improving bone metabolism.
A large number of literary studies have revealed the extensive pharmacological effects of β-ecdysterone in protein synthesis, glucose metabolism, central nervous system and skeletal development, and its molecular mechanism is very detailed. In addition, β-ecdysterone has become a potential therapeutic drug for many diseases, such as muscle wasting, diabetes, Alzheimer's disease, osteoporosis and other diseases. Beta-ecdysterone is currently widely used commercially.
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