Piperine Extract Powder Product Information
Piperine Extract Powder is the main active chemical substance in pepper, belonging to the cinnamon phthalimide alkaloid. It is widely found in nature, especially in the pepper family. It has been found that piperine has anti-oxidative, immunomodulatory, anti-tumor, and drug metabolism promotion effects.
In addition, processing pepper into piperine can increase the added value by 10 times. At present, piperine black pepper extract powder has a wide market in the world, and the economic benefits are very considerable.
COA of Piperine Extract Powder:
What is the extraction process of Piperine Extract Powder?
1. Acid water extraction of piperine
Most of the alkaloids have low solubility in water, and the acid water extraction prepared by HCL can convert the low solubility of piperine in pepper into the more soluble piperine salt and extract it. The operation method is as follows: pulverize the peppercorns and place them in a container, add a specified amount of acid water, decoct twice for 0.5 h each time, combine the filtrates and place them in a refrigerator, refrigerate for 12 hours, take out suction filtration, and place the filtrate in a refrigerator. Concentrate in a constant temperature water bath to extract, and then place it in a vacuum desiccator to vacuum dry to obtain piperine.
2. Use ethanol to extract piperine
Most alkaloids are soluble in ethanol, so ethanol can be used to extract piperine from the pepper. The operation method is: after crushing the peppercorns, add 10 times the amount of 75% ethanol, then reflux in a water bath to extract the filtrate, and finally evaporate the ethanol in the filtrate in a water bath to get piperine.
3. Supercritical Fluid Extraction (SFE)
SFE is the most versatile separation technique available today, enabling selective extraction from mixtures. First, the pepper raw material is loaded into an extraction vessel and then reacted with a supercritical solvent under relatively high pressure of 80-350Pa and a temperature of 35-70°C. The dissolved material and the supercritical solvent pass through the pressure-reducing valve, and the side pressure of the separator is about 40~60Pa, but the temperature is lower. Under these conditions, the solubility of the pepper material in the solvent decreased. When the raw material starts to separate, the gas is compressed and returned to extract the material, which can be recycled through the compressor.
What are the effects of piperine?
1. Anti-tumor effect
Piperine Extract Powder can inhibit B16F-10 melanoma-induced lung metastasis and significantly reduce tumor formation. It also effectively inhibits the gene expression of ATF-2, NF-kappab, and pro-inflammatory cytokines.
2. Antioxidant
Studies have shown that piperine has a certain antioxidant activity, and its antioxidant capacity is equivalent to 60.05% of vitamin C, and it exists stably in acidic media.
3. Effects on the central nervous system
Studies have shown that piperine has sedative, hypnotic, anticonvulsant, skeletal muscle relaxant, and antidepressant effects.
4. Immunomodulatory effect
piperine black pepper extract powder inhibits the production of reactive oxygen species (ROS) and increases glutathione (GSH) levels, and inhibits apoptosis and phenotypic changes in the-dependent lymphocytes.
5. Reduce inflammation
Oral administration of black pepper extract 95 piperine can significantly reduce inflammation. Piperine and its congeners are absorbed through the skin and therefore act on subcutaneous tissue, nerves, and blood vessels.
Where to buy Piperine Extract Powder?
Just through this website or send an email to medical@ysgcn.com, you can contact the most professional piperine manufacturer!
Hot Tags: piperine extract powder,piperine black pepper extract powder,black pepper extract 95 piperine,China, suppliers, manufacturers, factory, wholesale, quotation, low price, in stock, buy discount, free sample, made in China, , Natural Horse Chestnut Extract Powder
