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Tocopheryl Succinates

Tocopheryl Succinates

Product Name: DL-ALPHA-TOCOPHEROLHYDROGENSUCCINATE
Chemical formula: C33H54O5
Molecular weight: 530.7789
Content:1185IU, 1210IU
CAS accession number: 17407-37-3
EINECS Accession Number: 241-433-7
Melting point: 75 ℃
Boiling point: 625.84 ℃
Water solubility: insoluble in water. Soluble in chloroform. Soluble in acetone, ethanol, ether, and vegetable oil.
Density: 1.002 g/cm³
Appearance: Colorless to white crystalline powder. Odorless and tasteless

PRODUCT INTRODUCTION

PRODUCT INTRODUCTION

Tocopheryl Succinates Introduction:

Tocopheryl Succinates (TOS) are the product of the esterification of Tocopherol with succinic anhydride. It is an important ester derivative of tocopherol. Compared with tocopherol, its physical and chemical properties such as oxidation stability and surface activity are significantly improved. Has a unique pharmacological function. Thereby expanding the application field of tocopherol.

Under normal conditions, TOS is a white or off-white crystalline powder. Almost odorless and stable in the air. Insoluble in water, soluble in acetone, ethanol, ether, and vegetable oil, and easily soluble in chloroform.

 

TocopherylTocopheryl Succinates quotation

 

Item:

Value:

Appearance

White to off-white crystalline powder

Certified Kosher and IP, pass all USP and FCC tests

Yes

Bulk density

0.40-0.60g/ml

Melting point

73-78℃

Odor

Little or no odor

Acidity

18.0-19.3 ml

Potency, IU/g

Min.1162

Heavy Metals(as Pb)

Max.10ppm

Specific Rotation [a]d25, degrees

+24

Organic Volatile Impurities

Pass, USP<467>Method Ⅳ

Assy(alpha-tocopheryl succinate)

96%min.

Benz(a)Pyrene

Max.2ppb

 

Application in the Food Industry:

Its normal state is solid powder. Good stability, almost odorless, not easy to absorb moisture, not easy to contaminate bacteria, and will not be oxidized. It can fully meet the processing requirements of dry powder products for making tablets and hard capsules. In addition, using the carboxyl group introduced into the molecule, TOS can react with calcium hydroxide to produce calcium tocopheryl succinate. This calcium salt form of tocopherol derivatives has a melting point of up to 180°C. Good stability, easy to prepare tablets and capsules. As a nutritional fortifier in healthy food, vitamin E and calcium can be supplemented at the same time.

Good and stable physicochemical properties based on it and calcium tocopheryl succinate. In developed countries such as Europe, America, and Japan, it has become the most commonly used raw material in vitamin health food. Tocopherols are found in nearly all nutritional supplements in tablet and hard capsule form.

 

Yansheng International Group Ltd. is a professional China Tocopheryl Succinates factory. We have more than 16 years of production and R&D experience. To provide you with better products and services. is your trusted supplier.

If you are interested in it. Please contact us directly through this page or medical@ysgcn.com

 

Production Method:

Acetic acid is used as a solvent and anhydrous sodium acetate is used as a catalyst. In addition, zinc powder and acetic acid are added to the system to form a reduction system to avoid the oxidative loss of tocopherol. The reaction mixture was stirred at 100-140 °C for 2-8 h. The product was mixed with an appropriate amount of water and extracted with n-hexane. The d alpha tocopheryl succinate was washed with water, dried over anhydrous sodium sulfate, and filtered. The filtrate was concentrated under reduced pressure to obtain the crude succinic acid monoester of tocopherol. It was further purified by alumina chromatography to obtain a product with a purity of 99.5%.

 

In daily necessities?

Tocopheryl Succinates can be easily added to cosmetics. As an active ingredient with a moisturizing effect, it plays a role in preventing skin dehydration and aging. It can also be used as a functional additive of oral cleaners and applied to oral hygiene products. It can promote ulcer healing, fight inflammation, protect the gum base and prevent premature aging of periodontal tissue.

 

Why choose us?

1. More than 16 years of production and R&D experience

2. Insist on using better raw materials to produce better products

3. Standard processing and extraction process and strict quality inspection process

4. GMP-Standard Workshop

● 4 Stainless Steel Production Line Complied with GMP Standard

● 7 Concentration Facilities

● 36 Stainless Steel Chromatographic Separation Columns

● Spraying and Drying System

● Refining, Drying, and Packing workshop

● High-Temperature Sterilization workshop

5. All the ingredients are natural and approved BY ISO, KOSHER, HALAL, SC, HACCP approved, and FDA registered.

 

why choose us

 

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