COQ10 Ubiquinone Introduction
CQ10 Ubiquinone is a quinone compound widely present in body cells. Also known as Coenzyme Q, CoQ. A compound formed by combining a benzoquinone ring with multiple long chains of polyisoprene. The chemical name is 2,3-dimethoxy-5-methyl-6-polyprenyl-1,4-benzoquinone (trans configuration).
Similar in structure to fat-soluble vitamins, it is yellow or light orange-yellow crystalline powder at room temperature. The number of isoprenes in the side chain varies from organism to organism, and humans have 10, so it is also called coenzyme Q10 (CoQ10). There are 9 mice. 8 for E. coli; 6 for Saccharomyces cerevisiae). COQ10 Ubiquinone powder can be synthesized naturally or ingested through diet.
Specification
|
ANALYSIS |
SPECIFICATION |
RESULTS |
|
Assay (Anhydrous basis) |
98.0%-101.0% |
USP<621> |
|
Decription |
Yellow-orange crystalline powder |
Visual |
|
Melting Point |
48℃-52℃ |
USP<741> |
|
Solubility |
Soluble in ether;trichloroethane |
USP<1171> |
|
IR |
Sample spectrum consistent with the spectrum for USP Reference Standard |
USP<197K> |
|
Color reaction |
A blue color appears |
USP<197K> |
|
Sieve |
100%pass 80 mesh |
USP<786> |
|
90%pass 100 mesh |
USP<786> |
|
|
Tapped Density |
0.40g/ml~0.60g/ml |
USP<616> I |
|
Water(KF) |
≤0.2% |
USP<921> IC |
|
Residue on Ignition |
≤0.1% |
USP<281> |
|
Chromatographic Purity Coenzymes Q7,Q8,Q9,Q11 and related impurities |
≤1.0% |
USP<621> |
|
Ubidecarenone(2Z)-isomer and related impurities |
≤0.5% |
USP<621> |
|
Total impurities |
Total 1&2≤1.5% |
USP<621> |
|
Residual Solvents |
||
|
Methanol |
≤3000ppm |
USP<467> |
|
n-Hexane |
≤290ppm |
USP<467> |
|
Ethanol |
≤5000ppm |
USP<467> |
|
Isopropyl ether |
≤300 ppm |
USP<467> |
|
Heavy Metals |
||
|
Heavy Metal |
<10ppm |
USP<2232> |
|
As |
<1ppm |
USP<2232> |
|
Cd |
≤0.5ppm |
USP<2232> |
|
Pb |
≤ 0.5ppm |
USP<2232> |
|
Hg |
≤ 0.1ppm |
USP<2232> |
|
Microbial limit test |
||
|
Total Aerobic Microbial |
<1000cfu/g |
USP<2021> |
|
Yeast&Mold Count |
<50cfu/g |
USP<2021> |
|
E.Coli |
Absent/10g |
USP<2022> |
|
Salmonella |
Avsent/25g |
USP<2022> |
|
Bile-tolerant gram negative bacteria |
<1MPN/g |
USP<2021> |
|
Staphylococcus aureus |
Avsent/25g |
USP<2022> |
|
Pseudomonas aeruginosa |
Absent/10g |
USP<62> |
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Absorption and transport in animal organisms
CQ10 Ubiquinone is a lipophilic substance. Its absorption process is the same as that of lipids in the gastrointestinal tract. Absorption efficiency increases in the presence of lipids. It is mainly absorbed in the small intestine in a process similar to lipophilic substances such as vitamin E. It first enters the chylogranules and is transported to the circulatory system through the lymphatic vessels.
These microparticles are then converted into chylomicron remnants in the blood circulation by lipoprotein lipase. Rapidly absorbed by the liver. Lipoprotein complexes are formed in the liver. 58% of CoQ is transported by low-density lipoprotein (LDL). 26% is carried by high-density lipoprotein (HDL). The remaining 16% is carried by very low-density lipoprotein (VLDL). Then it is distributed to the myocardium, adrenal gland, lung and other tissues. In animals, about 95% of COQ10 Ubiquinone exists in reduced form in plasma). Through radioisotope research, it was found that the unabsorbed part was mainly excreted through bile and feces, and a small part was finally excreted with urine.
Efficacy in the field of pets
1. Adjuvant therapy for age-related diseases
Plays an important role in mitochondrial neutralization against oxidative stress. Anti-aging and adjuvant treatment of aging-related diseases has a positive effect. It is mainly reflected in the adjuvant treatment of pets' heart, blood pressure, blood sugar, bone and joints, and other age-related symptoms.
2. Promote fat metabolism
COQ10 Ubiquinone can prevent adipogenesis, inhibit the differentiation of adipocytes, and increase fat oxidation and energy consumption in adipose tissue.
3. Anti-fatigue, improve exercise ability
It can be used to help police dogs, search and rescue dogs and other working dogs and sports dogs recover their physical strength and protect their hearts after high-load work or exercise.
4. Healthy teeth and skin protection
Not only can it play the healthcare function of gum bleeding and oral ulcer healing. It can also pass through the gingival cell membrane to enable gingival cells to obtain energy and enhance tissue vitality. Fundamentally maintain the gums, prevent periodontitis, and gum recession, and achieve the purpose of healthy teeth.
On the one hand, it can improve the disease resistance of the pet body, making it less likely to be infected with such diseases. On the other hand, it helps the recovery of skin damage and wound healing due to diseases.
COQ10 Ubiquinone Application
COQ10 Ubiquinone can be directly used as a feed additive in pet feed and snacks. It can also be used to produce cleaning products such as toothpaste for pets. In addition, it can also be used to produce health products such as nutritional supplements that pets usually eat. It can also be used in combination with other drugs to produce pet medicines and preparations with corresponding functions. With the development of the pet industry and people's deeper understanding of ubiquinone. Its development in the pet industry is still worth looking forward to!
★Certificate:
All the ingredients are natural and approved BY ISO, KOSHER, HALAL, SC, and HACCP approved.
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