Ecdysterone is one of the most representative active ingredients of Cyanotis arachnoidea. It belongs to steroid hormones and has strong pharmacological activity. It can promote cell growth and wound healing, enhance human metabolic function, lower blood sugar, regulate blood lipids, antioxidant and clear Free radicals, improve liver function, anti-inflammatory and anti-rheumatic, inhibit tumors and protect cardiovascular and cerebrovascular.
Ecdysterone Benefits：
1. Anti-inflammatory and analgesic
The mechanism of ecdysterone's effective improvement of radioactive oral mucositis, anti-inflammatory, and analgesic in rats may be because most Commelinaceae plants contain plant ecdysterone, which has the effect of "diuresis, swelling, and pain relief".
2. Anti-tumor
Studies have found that ecdysterone can reduce metabolism and induce autophagy in different subtypes of breast cancer cell lines. Multidrug-resistant (MDR) cancer cells have enhanced sensitivity and activity with remarkable selectivity. β-ecdysterone has certain antitumor activity.
3. Affects metabolic function
It has a certain effect on glucose metabolism and lipid metabolism.
4. Neuroprotection
Ecdysterone can improve learning and memory function. The improvement of learning and memory dysfunction by ecdysterone may be related to the relative increase of ChAT activity in the cortex and hippocampus. Ecdysterone is neuroprotective against acute stress.
5. Cardiovascular effects
β-ecdysterone exerts cardiovascular protection by inhibiting apoptosis and oxidative stress, improving acute myocardial infarction, and other ways.
6. Organ protection
Studies have shown that injection of ecdysterone can significantly enhance the recovery ability of liver function and metabolic disorders, and can significantly stimulate the recovery of bile secretion, promote the synthesis of bilirubin and bile acids, and excretion of cholesterol, so phytoecdysterone has liver protection.
7. Skeletal Development
Promoting the proliferation and differentiation of bone cells, ecdysterone regulates bone development and affects bone diseases through various mechanisms.
In inhibition of bone cell apoptosis, studies have shown that β-ecdysterone attenuates apoptosis by promoting autophagy in nucleus pulposus cells, participates in the regulation of osteoblast autophagy, and promotes the expression of anabolic genes, β-ecdysterone may be a potential therapeutic agent for IDD.
Ecdysterone has always attracted much attention due to its prominent pharmacological action. In-depth research on its pharmacological action is conducive to the development of new medicinal uses and further elucidation of its pharmacological mechanism.
Ecdysterone has a variety of activities, especially anti-inflammatory, and anti-tumor, protecting the nervous system, lowering blood sugar and lipids, cardiovascular, skeletal system, and organ protection. Hyperlipidemia and the organ damage caused by it, anti-tumor, and treatment of cardiovascular and cerebral ischemia-reperfusion diseases are developed and utilized.
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