What is Bacopa Herb Extract?
Bacopa Herb Extract takes Bacopa Herb as raw material through professional extraction and separation. The final active ingredient is the brown powder of Bacopa saponin.
bacopa extract is cultivated as a characteristic wild vegetable. It hardly needs to be sprayed with pesticides during the whole growth period. It is a natural pollution-free vegetable. And taste all good, no special smell.
| Item | Bacopa Herb Extract |
| Spec./Purity | natural Pure powder |
| Appearance | Brown yellow powder |
| Package | 1Kg/Foil bag,25Kg/Drum |
| MOQ | 1KG |
| Delivery Time | 2-5 Working Days |
| Shelf Time | 2 year |
| Storage | Store in a dry and cool place, protected from light,heat and oxygen. |
What is the chemical composition of Bacopa Herb Extract?
1 Terpenoid
Since the 1960s, studies have found that Bacopa Monnieri contains a large number of terpenoids. At present, the terpenoids isolated from this plant are mainly triterpenoids, and most of them exist in the form of glycosides. So far, four main types of aglycone core structures have been found: dammarane, cucurbitane, lupinane, and ursane.
2 Flavonoids
The literature search found that Bacopa also contains some flavonoids, mainly flavonoids, and chalcones.
3 Phenylethanol glycosides
bacopa extract powder was reported in the literature that in 2002, Chakravarty et al. isolated a class of phenylethanoid glycosides from Bacopa Monnieri. In 2016, Japanese scholar Ohta et al. isolated 2 new phenoxyethanol glycosides from this plant.
4 Sterols
Sterols are a class of steroids derived from the biosynthetic pathway of glutaric acid. Bacopa Serrata plants have small amounts of these compounds.
5 Other types of compounds
In addition to the above-mentioned compounds such as triterpenes, flavonoids, phenethyl alcohol glycosides, and sterols, some other compounds were also isolated from this plant.
9 other compounds, such as aromatic compounds and α, β unsaturated lactone compounds, etc.
Pharmacological Activity of Bacopa Herb Extract:
Effects on the central nervous system
1. Enhance cognition, learning, and memory function
2. Antidepressant effect
3. Anti-anxiety effect
4. Anti-schizophrenia effect
5. Anti-Parkinsonian effect
6. Anticonvulsant and antiepileptic effects
7. Improve Autism
8. Protect brain mitochondrial function
9. Reduces morphine tolerance and withdrawal symptoms
Effects on the cardiovascular and cerebrovascular system
Bacopa Monnieri extract can prevent brain damage caused by ischemia and reduce the size of ischemic cerebral infarction; it also has the effects of anti-hypercholesterolemia, anti-platelet aggregation, thrombolysis, and increasing vascular endothelial cells.
Effects on the digestive system
1. Anti-ulcer effect
2. Smooth muscle spasm
3. Antiemetic effect
4. Ejaculation
Effects on the respiratory system
Bacopa Monnieri extract has bronchodilator activity and can also exert a relaxing effect on tracheal smooth muscle by blocking calcium channel activity.
Effects on the endocrine system
Can be used to regulate hypothyroidism.
Anti-oxidize effect
Antioxidant activity experiments in vitro showed that the methanol extract of Bacopa Monnieri had the ability to scavenge nitric oxide radicals, 1,1-diphenyl-2-picrohydrazine (DPPH) radicals, hydroxyl radicals, and superoxide radicals. The activity and reducing ability may be due to the fact that the methanol extract of Bacopa Monnieri contains more polyphenols, and the antioxidant activity of the leaf extract is significantly stronger than that of the root or stem extract.
Anti-inflammatory and analgesic effects
1. Anti-inflammatory effect
Growing evidence suggests that Bacopa Herb Extract inhibits cyclooxygenase-2, lipoxygenase activity, and the inflammatory cytokines tumor necrosis factor-alpha (TNF-alpha) and interleukin-6
(IL-6) release.
2. Analgesic effect
Bacopa Monnieri methanol extract significantly reduced the number of acetic acid-induced gastric contractions in a dose-dependent manner, and even the lowest dose of the extract (50 mg/kg) showed better analgesic activity than aspirin.
Antitumor effect
Studies have shown that bacoside A has the potential to protect endogenous enzymatic and non-enzymatic antioxidant activities, quench lipid peroxidation and enhance antioxidant status through free radical scavenging, thereby effectively preventing N-nitrosodiethylamine-induced Liver cancer occurs.
Liver and kidney protection
1. Liver protection
More and more studies have shown that Bacopa Serrata has a good protective effect on the liver, and its protective function may be attributed to its antioxidant effect.
2. Kidney protection
Bacopa Monnieri ethanol extract can increase the activity of enzymatic antioxidants such as SOD, CAT, GSH-Px, GST, and GR and non-enzymatic antioxidants such as GSH, vitamin C, vitamin E, up-regulate endothelial nitric oxide synthase (eNOS) ) and down-regulate the expression of iNOS gene, thereby exerting the effect of renal protection agent.
Hypoglycemic effect
Bacopa Monnieri methanol extract can significantly inhibit the increase of serum glucose concentration in a dose-dependent manner.
Antimicrobial effect
1. Antibacterial effect
2. Anti-Leishmania
Prospects of Bacopa Herb Extract:
At present, the types of compounds isolated from Bacopa Monnieri mainly include chemical components such as triterpenes and their glycosides, flavonoids, phenethyl glycosides, and sterols. Modern pharmacological studies have shown that Bacopa Serrata has certain effects on the central nervous system, cardiovascular, digestive, respiratory, endocrine, and other systems. It has a protective effect on the liver and kidney, and its pharmacological activities are mostly related to triterpenoid saponins, so the development of this plant has broad prospects.
Please contact us directly through this website or medical@ysgcn.com to purchase Bacopa Monnieri extract!
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