What is Pure Luteolin Powder?
Pure Luteolin Powder is a flavonoid found in plants such as winter plum blossoms. Different types or numbers of groups carried by flavonoids may cause differences in their physiological effects. The treatment of cardiovascular disease with luteolin may be a major breakthrough in the history of clinical cardiovascular disease drug treatment.
Specifications of Pure Luteolin Powder:
| Product Name | Pure Luteolin Powder |
| Specification | 98% |
| Appearance | light yellow powder |
| CAS NO. | 491-70-3 |
Benefits of Pure Luteolin Powder:
Antioxidant and anti-inflammatory properties, which can reduce chronic inflammation by eliminating reactive oxygen species and inhibiting the NF-κB pathway. Studies have found that it is better than salicylic acid in alleviating colitis.
Neuroprotective effects, enabling it to cross the blood-brain barrier and inhibit the aggregation of beta-amyloid protein. Animal studies have found that it can improve cognitive function.
Anti-allergic and immunomodulatory effects, capable of blocking histamine H1 receptors and relieving hay fever symptoms.
Antitumor potential, targeting the PI3K/AKT pathway to inhibit breast cancer cell metastasis.
Promotes necessary proactive system balance, helping to achieve a positive balance within the body. This can support the immune system, increase stamina, support circulation, improve sleep quality, naturally detoxify, clear the skin, enhance mental alertness, boost energy, and improve mood.
Provides skin conditioning benefits. When used in cosmetic formulations, it helps maintain skin softness, smoothness, and hydration, supports the skin's natural barrier to lock in moisture and protect against environmental stressors. It is particularly beneficial for dry and sensitive skin.
Protective effect of luteolin on myocardial ischemia-reperfusion injury
Luteolin activates PI3K/Akt signaling pathway
The first step of the cardioprotective effect of luteolin on hypercholesterolemia I/R is to activate the PI3K/Akt signaling pathway, and then inhibit GSK3β/Fyn, thereby gradually starting the activation and nuclear translocation of Nrf-2, and up-regulating HO-1 and other antioxidant genes and inhibit the opening of mPTP associated with oxidative stress. The activation of Nrf-2 and HO-1 both have protective effects on I/R. When I/R occurs, a large amount of intracellular Ca2+ accumulation, massive production of reactive oxygen species, and nitric oxide synthase (eNOS) dysfunction, their interaction promotes the opening of mPTP and further aggravates I/R. Luteolin can inhibit the opening of mPTP and reduce I/R. R
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Luteolin inhibits the TLR-4/NF-κB signaling pathway
wholesale pure luteolin powder can reduce the expression levels of TLR-4 and NF-κB in I/R, suggesting that luteolin can improve I/R through this pathway.
The anti-heart failure effect of luteolin
Luteolin down-regulates the expression of P53 protein
Luteolin pretreatment reversed the reduction in the anti-apoptotic mediators Bcl-2 and Akt, while the expression of the pro-apoptotic proteins Bax, Caspase-8, Cleaved-Caspase-3, and p53 was increased.
Where to buy Pure Luteolin Powder?
Yansheng International Group Ltd. is one of the best luteolin manufacturers. You can contact us directly for luteolin, or buy it directly through medical@ysgcn.com
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