Pure Piperine Product Information
Pure Piperine alias 1 - piperonyl piperidine, piperine amide, is an amide alkaloid compound isolated from the fruits of pepper, piper, and other piperine plants, and plays the main biological activity.
Pure Piperine Powder contains spicy components and is commonly found in a variety of everyday foods and seasonings. It exists widely in nature, especially in the Piperaceae plant. It is grown in Yunnan, Hainan, and other regions of China. piperine extract powder is also a scientifically proven biological enhancer, which can improve the bioavailability of dual-purpose drugs, herbal ingredients, and nutrients. , its pharmacological action is more extensive.
Physical and chemical properties and composition:
Pure Piperine is a nitrogen-containing alkaloid, white crystalline powder; melting point 131~135℃; soluble in acetic acid, benzene, ethanol, and chloroform, slightly soluble in ether; molecular formula: C17H19NO3; the molecular weight is 285.34 g mol﹣¹, its structure is composed of 3 subunits: (1) an amide group consisting of a piperidine ring containing a-b-unsaturated carbonyl; (2) 1,3-phenyldioxyl, also known as piperonic acid nucleus; (3) Butadiene chain. Piperine has 4 configurational isomers, namely piperine (trans isomer), isocarvicine (trans-cis isomer), and savixin (cis-cis isomer). isomer) and isopiperine (cis-trans isomer); of which piperine has the strongest activity and highest medicinal value, and the other three geometric isomers have almost no pharmacological activity.
Toxicology and safety:
Currently, chemotherapy is mainly limited to genotoxic drugs that have severe side effects due to their non-selective targeting of normal tissues. Natural Pure Piperine plays an important role in the development of most chemotherapeutic drugs, and 74.8% of the available chemotherapeutics are derived from natural products. It has been reported in the literature that piperine extract effectively and selectively inhibits and induces the viability of cancer cells in a dose- and time-dependent manner, without associated toxicity.
piperine extract powder has been used in the traditional pharmacopeia for many years and the best experimental model has not shown genotoxic effect in vitro or in vivo. Generally safe at doses close to daily food intake, it can significantly reduce the carcinogenic risk of various chemical carcinogens to animals.
As the main bioactive compound, piperine has been found to have many potential therapeutic applications, such as anticancer, antibacterial, anti-inflammatory, antioxidant, and other pharmacological activities, and has also been widely used to improve the bioavailability of drugs and nutrients. focus on.
As a pharmaceutical ingredient with abundant raw materials and wide application, piperine has shown its application value in medicinal chemistry and biomedicine both in traditional medicine and modern pharmacology. Some clinical trials have demonstrated the safety and efficacy of piperine in the human body, so it is of great significance to further develop the application of piperine extract of longan and its synergistic effect with other organic components.
Yansheng International Group Ltd. always insists on BETTER INGREDIENTS BET TER FOR YOUR LIFE! is one of the best piperine manufacturers, you can directly contact us to buy piperine, of course, the mail is also possible, just send it to medical@ysgcn. com
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