What is Caffeic Acid Powder?
Caffeic Acid Powder, also known as 3,4-dihydroxycinnamic acid. Exist in Solidago (Compositae), Shanlihong (Rosaceae), Polius (Sapindaceae), Cimicifuga (Ranunculaceae), Eurasian water keel (Water keel family), Lemon (Rutaceae), Coccidium (Polyaceae) , Valerian (Sorrelaceae), Thyme (Lipaceae), Eucommia (Eucommia ulmoides) and other Chinese herbal medicinal plants. It has the function of shrinking and strengthening microvessels and promoting the role of coagulation factors. Increase the efficacy of white blood cells and platelets for treating white blood cells and thrombocytopenia.
Item | Value |
Product name | Caffeic Acid |
Form | Powder |
Specification | 99% |
Color | light yellow powder |
Packaging | bottle, DRUM, Glass Container, Plastic Container, Vacuum Packed |
Place of Origin | China Shaanxi |
How to extract Caffeic Acid Powder?
The process of extracting refined caffeic acid from cohosh is as follows:
The rhizomes of single spike cohosh need to be extracted with methanol and then concentrated under reduced pressure to remove methanol. The residue was dissolved in heated water, and the insoluble was removed by filtration while hot. After cooling, benzene was added for extraction, and the benzene solution was washed with 1% aqueous sodium bicarbonate solution, and the washings were collected. Add dilute hydrochloric acid for acidification, use benzene to free organic acid from it, and concentrate under reduced pressure to remove benzene, and the residue is the enriched product of caffeic acid.
The process of extracting refined caffeic acid from Cirsium arvense var. integrifolium is as follows: 50 g of crude artichoke (dry basis), add 500 mL of water and decoct for 0.5 h, and combine 2 decoctions. After suction filtration, the filter residue was discarded. The filtrate was brown, heated in an electric furnace, and concentrated to 400 mL. After cooling, it was extracted with ethyl acetate, and the water sample was retained. Then remove with n-butanol, retain the water sample, precipitate with 95% ethanol, suction filtration, and the solution is reddish-brown. Concentrate under reduced pressure to 150 mL, add water to dissolve to 250 mL, and precipitate with saturated lead acetate solution. In suction filtration, the precipitation is khaki, delead with 10% sulfuric acid, In suction filtration, the solution is adjusted to pH 6 with 6% potassium hydroxide solution, and the crystallization is concentrated. Recrystallize with water, and after standing for 2 hours, large rod-shaped crystals are precipitated, and the product can be obtained by drying.
What are the benefits of Caffeic Acid Powder?
1. Litre of white blood cells, platelets, and anti-platelet aggregation
Caffeic acid has the functions of constricting microvessels, enhancing the level of coagulation factors, and increasing white blood cells, platelets, and hemostasis.
2. Antioxidant
Can effectively inhibit lipid peroxidation of linoleic acid emulsion. And it has stronger reducing power than α-tocopherol (α-tocopherol), tert-butylhydroxyanisole (BHA), dibutylhydroxytoluene (BHT), and water-soluble vitamin E (Trolox).
3. Brain protection
caffeic acid bulk has anti-brain damage and senile dementia and other neurological diseases.
What are the problems of caffeic acid and how to improve it?
The main problems are that the oral absorption is not good, the bioavailability is low, and the drug effect cannot be fully exerted.
Improve methods:
1: Use modern preparation technology to improve its solubility and improve oral bioavailability.
2: Chemical modification is performed on it. to improve its bioavailability and biological activity. In addition, the stability of caffeic acid is poor, and it is easily converted and degraded in the body, which affects the curative effect. Therefore, caffeic acid bulk can be considered to combine caffeic acid with a suitable carrier to make a prodrug, so that it can release caffeic acid in a timely manner in the body and improve bioavailability.
Where to buy Caffeic Acid Powder?
Yansheng International Group Ltd. provides you with high-quality caffeic acid and other products. We escort you with more than sixteen years of production experience. Please contact us directly through this website or medical@ysgcn.com
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