What is Lotus Leaf Alkaloid?
Lotus leaf extract is one of the main active ingredients in lotus leaf. Nuciferine is an aporphine alkaloid derived from the dried leaves of the water lily plant lotus. Clinical studies have found that Chinese herbal prescriptions based on lotus leaf can significantly reduce blood lipid levels, and have significant effects on the treatment of fatty liver, weight loss, and improvement of insulin resistance.
| Product Name | Nuciferine |
| Specification | 98% |
| Appearance | White powder |
| CAS NO. | 475-83-2 |
Features of Lotus Leaf Alkaloid:
Lotus leaf base is a kind of white powder with a relative molecular weight of 295.38, slightly soluble in water. The order of solubility in different polar solutions from small to large is: water < petroleum ether < n-octanol < acetone < methanol < ethyl acetate < ethanol < dichloromethane. Due to its low solubility in water, sodium carboxymethyl cellulose (CMC-Na) and lactic acid are often added to assist in the evaluation of drug efficacy. To facilitate the administration of experimental animals by gavage. Or first dissolved in dimethyl sulfoxide (DMSO), methanol, and ethanol to prepare a mother solution, and then dilute to the target concentration for in vitro experiments.
Lotus Leaf Alkaloid and Weight Loss:
Lotus leaf has a long history as a good fat-reducing product. It has been widely used in medicines and health care products that assist in regulating blood lipids. Lotus leaf alkaloid is one of the main medicinal components in lotus leaf, and its pharmacological activities and mechanism of lipid-lowering, weight loss, and liver protection have also been reported.
In animal models of obesity or hyperlipidemia induced by a high-fat diet, it can significantly inhibit the increase of body weight of model animals. Decrease Lee's index. Decreases liver index, epididymal fat, and perirenal fat mass. Improves fatty degeneration of liver tissue. Increase liver lipase and lipoprotein lipase activity. Down-regulation of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL-C), Free fatty acid (FFA) levels 15236-39.41 regulate the expression of lipid metabolism-related genes or proteins SREBP-1c, SREBP2, PPARa.PPARγ.CPT-1A.CD36.LXR-a, HMGCR, ACC, CYP7A1, FAS, SCD-1.
china lotus leaf extract has good pharmacological activities in regulating lipid metabolism and glucose metabolism, regulating bone metabolism, protecting nerves, and relaxing blood vessels and trachea. The mechanisms involve anti-inflammatory, antioxidant, intervening cell cycle and apoptosis, regulating intestinal flora, acting on ion channels, etc. Has good development prospects. If you want to buy Nuciferin, please contact us directly through this page or medical@ysgcn.com
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