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Capsaicin

Capsaicin

Capsaicinoids, which are the major pungent chemical found in Capsicum-genus plants like chilies, are phenolic compounds that share a vanilloid ring. Capsaicinoids consist of capsaicin, nordihydrocapsaicin, homocapsaicin, dihydrocapsaicin, and homodihydrocapsaicin, of which capsaicin has the highest prevalence. Capsaicin is associated with numerous health benefits including anti-inflammatory, anti-carcinogenic, anti-obesity agent, and antioxidant properties.

PRODUCT INTRODUCTION

PRODUCT INTRODUCTION

What is Capsaicin

 

 

Capsaicinoids, which are the major pungent chemical found in Capsicum-genus plants like chilies, are phenolic compounds that share a vanilloid ring. Capsaicinoids consist of capsaicin, nordihydrocapsaicin, homocapsaicin, dihydrocapsaicin, and homodihydrocapsaicin, of which capsaicin has the highest prevalence. Capsaicin is associated with numerous health benefits including anti-inflammatory, anti-carcinogenic, anti-obesity agent, and antioxidant properties.

 

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Our products have passed the US FDA registration, Kosher certification, Halal certification, ISO9001 certification, HACCP certification, and have obtained SC production license, health food business license, and export food production enterprise registration.

Our Factory

The factory is the more than 16 years GMP standard leading manufacturer of botanical extracts. Our products sets were covered with the area of 26,000 m², and have 4 lines for the productions, all raw materials, semi products, as well as the finished products will be checked before using.

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Our products will be regularly sent to third-party laboratories for proofreading and testing of items including content, moisture, ash, heavy metals, solvent residues, pesticide residues, proteins, microorganisms, etc., to ensure that our products are safe and meet customer needs.

 

Mogroside Ⅴ Monk Fruit

Mogroside Ⅴ Monk Fruit

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Allulose Powdered Sugar

Allulose Powdered Sugar

Particle Size:30-60 Mesh
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Pure Beta-Glucan

Spec./Purity:70% soluble in water
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Particle Size:30-60 Mesh
Appearance: White Granular
Specification: 99%
Test Method: HPLC
Sample Free: Sample
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Certifications: ISO, KOSHER, HACCP, HALAL...

Sweetener Allulose

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Particle Size:30-60 Mesh
Appearance: White Granular
Specification: 99%
Test Method: HPLC
Sample Free: Sample
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Pyrroloquinoline Quinone Powder

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Appearance: Reddish Brown Powder
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Test Method: HPLC
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PQQ Bulk Powder

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Organic Sesame Powder

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Appearance: Black powder
Specification: Straight Powder
Active Ingredients: Protein
Certificate: TLC
OEM Service: Customized as per guests' request
Sample: Available
MOQ:1kg
Storage: Cool dry place
Shelf life:2 years

Ginkgo Leaf Powder

Ginkgo Leaf Powder

Product Code: YSG-S-001
Used Part: Leaf
Active ingredients: Ginkgo flavone glycosides, Terpene Lactones, Ginkgolic Acid
Specification: 24/6/5 24/6/1
Test Method: By HPLC
Appearance: Yellow-brown powder
Certifications: ISO, KOSHER, HACCP, HALAL...

 

Capsaicin Health Benefits

 

Relives Pain
Capsaicin extract provides relief from pain in ailments such as in osteoarthritis, migraines, sinus aches, shingles, postherpetic neuralgia pain, rheumatoid arthritis, neuropathic pain, complex pain and migraine.

 

Prevents Cancer
The consumption of capsaicin can contribute in treating certain cancers such as prostate cancer by keeping carcinogens away from getting imbibed with DNA.

 

Inflammatory Diseases
Capsaicin is an extremely effective anti-inflammatory agent. It can help in diseases such as arthritis, diabetic neuropathy and psoriasis.

Weight Loss

This extract is highly beneficial in accelerating metabolism thus leading to weight loss. Fat burning supplements also consist of Capsaicin as a main ingredient.

Keeps Heart Healthy

Capsaicin also helps in keeping cholesterol under control, which leads to a healthy heart.

Relief from Sinusitis and Respiratory Ailments

Laden with antibacterial properties, Capsaicin is effective in clearing mucus, which proves highly beneficial in healing sinusitis, asthma, and clearing congestion.

Beneficial in Intestinal Diseases

 

Capsaicin extract works in intestinal disorders such as stomach pain, diarrhoea and cramps.

 

Evaluation of Carotenoid and Capsaicinoid Contents in Powder of Red Chili Peppers During One Year of Storage
 
 

The color and the pungency of red chili pepper powder, depending on the carotenoid and capsaicinoid contents, are important properties for this food ingredient. In this study the patterns of these two classes of compounds have been analyzed in samples of red chili powder during one year of storage at room temperature (20–24 °C) and at low temperature (− 18 °C), in order to investigate the eventual chemical changes occurring during storage, and to find a possible correlation between the behavior of the two groups of molecules.


During storage at room temperature, both carotenoid and capsaicinoid amounts were found to decrease progressively following a linear kinetics. After 12 months free carotenoids decreased to 20% of the initial value, and total capsaicinoids to 75%. All classes of carotenoids were found to be highly correlated with total capsaicinoids, thus showing that the molecules as the object of the study were subjected to similar kinetics. During storage at low temperature carotenoids decrease with lower rate (free carotenoids reached 66% of the initial value after 12 months) and capsaicinoids were almost unaltered.

 

Tips for Increasing Capsaicin in Your Diet
 

Building up your tolerance can mean you experience fewer side effects when eating very spicy foods.

Go for mild peppers

If you are not used to spicy foods at all, start with only mildly spicy peppers, such as pasilla chilies. Mild chilies will give a slight tingle and often a welcome fruitiness to a dish.
Remove the seeds:You can also reduce the heat in chili peppers by removing the seeds and veins - the white portion on the inside of the pepper - because these parts contain the highest concentration of capsaicin.

Go sweet

Last, temper your chili intake by combining it with naturally sweet or sour foods, such as by adding hot peppers to mango salsa. The sugar from the mango and the sourness of the lime juice will alter the taste of the chili. Acids boost the natural fruitiness and brightness of chilies, while sugar helps mellow out their heat.

 

Capsaicin Side Effects

 

Warmth, stinging, or burning on the application site may occur. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.

 

Coughing, sneezing, watery eyes, or throat irritation may occur if you breathe in the dried residue from the medication. Use caution to avoid inhaling the residue.

 

If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

 

Stop using this medication and tell your doctor right away if you have any serious side effects, including: blistering/swelling at the application site, increased/unusual pain at the application site.

 

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

 

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

 

How To Take Capsaicin

 

 

Capsaicin can be used in different ways. The plant compound naturally occurs in whole foods like chili peppers and cayenne powder, which can be consumed by mouth.


Capsaicin can also be consumed as an oral supplement, either in capsule or extract form. While doses of up to 200 milligrams per day have been used, there are no standard dosing guidelines for capsaicin supplements at this time (nor is oral capsaicin supplementation recommended for general health benefits).


Capsaicin is most effective when used topically-as a cream, gel, lotion, or patch-for pain relief. The amount of capsaicin in these products can vary, from 0.01% in creams and gels to about 8% in patches.


Nasal sprays containing capsaicin are sometimes used for treating allergies and cluster headaches, however more research on the efficacy of these treatments is needed.


Speak with your health care provider before starting capsaicin-based topicals or supplements.

 

Is Capsaicin Safe
 

Capsaicin is generally considered safe when consumed in the amounts that occur naturally in spicy foods such as chili peppers.


It is also generally well tolerated when used in over-the-counter (OTC) form or as prescribed by a healthcare provider.


However, long-term use of high-dose oral capsaicin supplements may pose potential health risks, including organ damage and dangerous high blood pressure.


Oral capsaicin supplementation is also not recommended for children or those who are pregnant or breastfeeding.


Always check with your healthcare provider before starting a new supplement to make sure the active ingredients are safe and the dosage is appropriate.

 

What are the applications of using Capsaicin
 

As a food additive: Chili peppers are used as food seasonings, and some shallow processing of chili peppers is required to make chili sauce and so on. However, when these products are eaten, the capsaicin has to undergo a leaching process, and the bioavailability of capsaicin is not high. At the same time, the alkali continues to be released in the intestine, irritating the intestinal wall, which can cause abdominal discomfort, and even cause anal burning pain and induce hemorrhoids. Therefore, the extraction and separation of capsaicin from capsicum, as an additive in food processing, is beneficial to the control of spiciness and the full absorption and utilization of capsaicin.

 

In terms of medicine and health care: My country is one of the earliest countries to use chili peppers as medicines. Chili peppers are used in traditional Chinese medicine to treat stomach cold and rheumatism. Modern research shows that capsaicin has anti-inflammatory, analgesic, anesthesia and detoxification effects. Its analgesic effect is equivalent to that of morphine, but it is more durable than morphine. It is effective in postherpetic neuralgia, trigeminal neuralgia, and diabetic neuralgia , rheumatoid arthritis, osteoarthritis, psoriasis, alopecia, etc. have significant curative effect. In addition, capsaicin can also inhibit the occurrence of malignant tumors, and also has special effects on the treatment of skin diseases and weight loss.

 

Applied to marine antifouling coatings: Some attached organisms in the ocean, such as barnacles, seaweed, shellfish, etc., are largely attached to the bottom of ships, buoys, wharves, bridge piers, seawater pipelines and aquaculture cages and nets. It is huge and grows very fast, which can slow down the speed of ships, increase fuel, accelerate metal corrosion, block pipes and cage meshes, and unbalance underwater facilities, causing great harm to human development of the ocean. Capsaicin is used as a repellant , has a strong repelling effect, and does not kill marine life, has obvious ecological benefits.

 

As an anti-ant and anti-rat repellent in wire and cable: PVC and polyethylene are more and more widely used as insulation and sheathing materials in the wire and cable industry. In addition to being damaged by oxygen, heat, light, force and chemical erosion In addition, it will also be damaged by termites, mice or hares, resulting in power outages, communication interruptions, and even short circuits, causing fires. Using the strong spicy taste of capsaicin, the oral mucosa and taste nerves of rodents can be strongly stimulated. And abandoning chewing, while killing termites, has broad application prospects in wire and cable.

 

Extracting Pure Capsaicin

To obtain pure capsaicin, one must go through a rigorous extraction process. There are several methods for extracting pure capsaicin, but the most common one is through organic solvent extraction, where pure capsaicin is separated from the pepper by dissolving it in a solvent. Here's a simplified breakdown of the process on extracting pure capsaicin:

 

Harvesting

The first step involves harvesting the hottest chili peppers available, such as the Carolina Reaper or the Trinidad Moruga Scorpion for extracting pure capsaicin.

Drying

The harvested peppers are dried thoroughly to remove excess moisture, making them easier to work with for extracting pure capsaicin.

Grinding

The dried peppers are ground into a fine powder from extracting pure capsaicin.

Solvent Extraction

The ground pepper powder is mixed with a solvent, often ethanol, which dissolves the pure capsaicin and leaves behind other components.

Evaporation

The solvent is then evaporated, leaving behind the concentrated pure capsaicin extract.

Purification

The crude pure capsaicin extract may require further purification to isolate pure capsaicin from other compounds, including waxes and pigments for extracting pure capsaicin.

Testing

The final product is rigorously tested to determine its pure capsaicin concentration and ensure it meets safety standards.

 

Neurobiology of Capsaicin-Induced Analgesia for Chronic Pain

 

 

Capsaicin, the pungent ingredient in chili peppers, produces intense burning pain in humans. Capsaicin selectively activates the transient receptor potential vanilloid 1 (TRPV1), which is enriched in nociceptive primary afferents, and underpins the mechanism for capsaicin-induced burning pain. Paradoxically, capsaicin has long been used as an analgesic. The development of topical patches and injectable formulations containing capsaicin has led to application in clinical settings to treat chronic pain conditions, such as neuropathic pain and the potential to treat osteoarthritis. More detailed determination of the neurobiological mechanisms of capsaicin-induced analgesia should provide the logical rationale for capsaicin therapy and help to overcome the treatment's limitations, which include individual differences in treatment outcome and procedural discomfort. Low concentrations of capsaicin induce short-term defunctionalization of nociceptor terminals. This phenomenon is reversible within hours and, hence, likely does not account for the clinical benefit. By contrast, high concentrations of capsaicin lead to long-term defunctionalization mediated by the ablation of TRPV1-expressing afferent terminals, resulting in long-lasting analgesia persisting for several months. Recent studies have shown that capsaicin-induced Ca2+/calpain-mediated ablation of axonal terminals is necessary to produce long-lasting analgesia in a mouse model of neuropathic pain. In combination with calpain, axonal mitochondrial dysfunction and microtubule disorganization may also contribute to the longer-term effects of capsaicin. The analgesic effects subside over time in association with the regeneration of the ablated afferent terminals. Further determination of the neurobiological mechanisms of capsaicin-induced analgesia should lead to more efficacious non-opioidergic analgesic options with fewer adverse side effects.

 

Our Factory
 

 

Xi'an JinRui International trade ltd. Founded in Hong Kong in 2010, YSG is a holding company of one companies.The company is Sanyuan Jinrui Natural Ingredients Co., Ltd., a company dedicated to the research, development and production of professional and specialized plant extracts. Jinrui's production and process base is located inside the Sanyuan County Qinghe Food Industrial Park. Established in 2006, the base occupies a plot of 26,000 square meters and takes full advantage of the "plant gene database" that is the nearby Qin Mountains. Using plants as natural raw materials and cutting-edge technology for the extraction process, Jinrui is well-known as one of the country's foremost plant extraction producers.

 

 

Certifications
 

 

All the ingredients are natural and approved BY ISO, KOSHER, HALAL, SC, HACCP approved, and FDA registered.

 

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FAQ

 

Q: What does capsaicin do to the body?

A: Capsaicin -- the chemical behind the zing -- amps up the rate at which your whole body heats up. It also activates a sensory neuron called TRPV1, which helps keep fat from building up and controls your appetite. This metabolism-quickening combo might help you lose weight.

Q: What foods are high in capsaicin?

A: Capsaicin is a lipophilic compound that can be found in different concentrations in peppers that are described as hot, such as Habanero, Jalapeño, and Scorpion. It is a compound that produces a burning sensation in any tissue it comes into contact with.

Q: What does capsaicin do to the nerves?

A: This study demonstrates that topical capsaicin, applied in a 48 hour occlusive dressing, leads to cutaneous autonomic nerve fiber injury with associated functional impairment. Capsaicin was previously shown to cause reversible changes in sensory nerve fiber structure and function.

Q: What does capsaicin do to your bowels?

A: An increased rate of digestion in the intestines that can lead to diarrhea. Nausea and vomiting (usually only if the food is very spicy). Painful bowel movements. Capsaicin is never entirely digested, so a portion will pass through the gut and trigger more TRPV1 pain receptors.

Q: Can capsaicin help you lose weight?

A: Capsaicin is believed to boost your metabolism by roughly eight percent on average. It increases metabolism and promotes weight reduction through thermogenesis (the process of heat production by the body). Hot peppers generate responses such as redness and perspiration through thermogenesis.

Q: Is cayenne pepper the same as capsaicin?

A: Cayenne peppers are long, thin, red peppers commonly used to spice up food. They contain nutrients such as vitamins A, C, and E, and many minerals that the body requires. The active compound in cayenne pepper is capsaicin, the substance that causes a burning sensation when we eat it.

Q: What happens if you use too much capsaicin?

A: Although it is often used in cooking, eating too much capsaicin can lead to irritation of the mouth, stomach, and intestines. People may develop vomiting and diarrhea. Inhaling sprays containing capsaicin can cause coughing, difficulty breathing, production of tears, nausea, nasal irritation, and temporary blindness.

Q: Is capsaicin anti-aging?

A: Some early research indicates that capsaicin has antioxidant properties that may help slow signs of aging on the skin, such as wrinkles and sagging skin (7).

Q: Is capsaicin a good anti-inflammatory?

A: It's been used both topically and orally to treat pain associated with conditions like osteoarthritis and chronic muscle pain, among others. In addition to bringing heat to your meals, capsaicin helps relieve pain and fight inflammation in the body.

Q: Can you use capsaicin everyday?

A: Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day. This medication may sometimes take up to 2 months to work. Tell your doctor if your condition lasts for more than 7 days, if it gets worse, or if it keeps returning.

Q: Is capsaicin good for back pain?

A: Capsaicin cream has beneficial effects on pain relieving and reducing analgesic use in patients with inter-vertebral disc herniation. Therefore, the ointment can be recommended in the treatment of low back pain caused by inter-vertebral disc herniation.

Q: Is capsaicin safe for kidneys?

A: Additionally, capsaicin may serve as a protective factor against different types of kidney injuries and diseases, including hypertension, which endorses this molecule as a potential renoprotective agent, besides the traditional therapies, where available.

Q: Does capsaicin anti-inflammatory?

A: Capsaicin in both forms (CFE and CPF) produced anti-inflammatory effects that were comparable to diclofenac in the experimental rat model at p<0.05. It may be concluded that capsaicin has both analgesic and anti-inflammatory properties.

Q: What does capsaicin do to the tongue?

A: The substance in a chilli pepper that causes the burning sensation in your mouth is called capsaicin. It binds to a receptor in your mouth and on your tongue called TRPV1 – the same receptor that tells you when something on your skin is too hot.

Q: Why does capsaicin make me feel high?

A: This compound centers around the tongue, causing an intense burning sensation. Throughout all the pain associated with spicy foods, the consumption of these foods releases endorphins and dopamine. This creates euphoria similar to a "runners high."

Q: How do you flush capsaicin?

A: "Rinsing your mouth with anything is better than nothing," Dr. Rood says, "but only milk and Kool-aid outperformed plain water." Milk contains a protein called casein, which can break down capsaicin - much in the same way that dish soap can cut through grease.

Q: Is capsaicin good for health?

A: Capsaicinoids consist of capsaicin, nordihydrocapsaicin, homocapsaicin, dihydrocapsaicin, and homodihydrocapsaicin, of which capsaicin has the highest prevalence. Capsaicin is associated with numerous health benefits including anti-inflammatory, anti-carcinogenic, anti-obesity agent, and antioxidant properties.

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